Mitochondria have been increasingly recognized as the important players in the aging
process. Most aging-related diseases, particularly, neurodegenerative diseases, have …

Aging is a natural biological process in living organisms characterized by receding
bioenergetics. Mitochondria are crucial for cellular bioenergetics and thus an important …

Aging is accompanied by a time-dependent progressive deterioration of multiple factors of
the cellular system. The past several decades have witnessed major leaps in our …

Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

The aging process is accompanied by the onset of disease and a general decline in
wellness. Insights into the aging process have revealed a number of cellular hallmarks of …

Mitochondria are best known as the sites for production of respiratory ATP and are essential
for eukaryotic life. They have their own genome but the great majority of the mitochondrial …

Mitochondria perform diverse yet interconnected functions, producing ATP and many
biosynthetic intermediates while also contributing to cellular stress responses such as …

Mitochondrial dysfunction entailing decreased energy‐transducing capacity and perturbed
redox homeostasis is an early and sometimes initiating event in ageing and age‐related …

Mitochondria are eukaryotic organelles known best for their roles in energy production and
metabolism. While often thought of as simply the 'powerhouse of the cell,'these organelles …

Mitochondria were described as early as 1890 as ubiquitous intracellular structures by
Ernster and Schatz (1981)[1]. Since then, the accretion of knowledge in the past century has …