[HTML][HTML] Loss of CDH16 expression is a strong independent predictor for lymph node metastasis in Middle Eastern papillary thyroid cancer
AK Siraj, SK Parvathareddy, M Al-Rasheed… - Scientific Reports, 2023 - nature.com
Abstract Papillary Thyroid Cancer (PTC) is the most common type of thyroid cancer. The
membrane-associated glycoprotein cadherin-16 (CDH16) plays a significant role in the …
membrane-associated glycoprotein cadherin-16 (CDH16) plays a significant role in the …
[HTML][HTML] Cadherin‑16 inhibits thyroid carcinoma cell proliferation and invasion
X Yang, Y Li, G Liu, W Zha, Y Liu - Oncology Letters, 2022 - spandidos-publications.com
Abstract Cadherin‑16 (CDH16), a member of the cadherin family of adhesion molecules,
serves an important role in the formation and maintenance of the thyroid follicular lumen …
serves an important role in the formation and maintenance of the thyroid follicular lumen …
Downregulation of CDH16 in papillary thyroid cancer and its potential molecular mechanism analysed by qRT-PCR, TCGA and in silico analysis
P Li, Q Wu, Y Sun, X Pan, Y Han, B Ye… - Cancer Management …, 2019 - Taylor & Francis
Objective Thyroid cancer has the highest prevalence among the cancer types that affect the
endocrine system; however, its molecular mechanisms are not yet determined. Cadherin-16 …
endocrine system; however, its molecular mechanisms are not yet determined. Cadherin-16 …
[HTML][HTML] Cadherin-16 (CDH16) immunohistochemistry: A useful diagnostic tool for renal cell carcinoma and papillary carcinomas of the thyroid
M Lennartz, H Csomós, V Chirico, S Weidemann… - Scientific Reports, 2023 - nature.com
Abstract Cadherin-16 (CDH16) plays a role in the embryonal development in kidney and
thyroid. Downregulation of CDH16 RNA was found in papillary carcinomas of the thyroid. To …
thyroid. Downregulation of CDH16 RNA was found in papillary carcinomas of the thyroid. To …
[HTML][HTML] Downregulated CDH3 decreases proliferation, migration, and invasion in thyroid cancer
Y Zhou, Y Chi, A Bhandari, E Xia… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Background: Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the
function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly …
function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly …
[HTML][HTML] Cytosolic Cadherin 4 promotes angiogenesis and metastasis in papillary thyroid cancer by suppressing the ubiquitination/degradation of β-catenin
L Wu, J Xiao, D Yi, H Ding, R Wang, Z Duan… - Journal of Translational …, 2024 - Springer
Background Although the long-term prognosis of papillary thyroid cancer (PTC) is favorable,
distant metastasis significantly compromises the prognosis and quality of life for patients with …
distant metastasis significantly compromises the prognosis and quality of life for patients with …
CDH16/Ksp-cadherin is expressed in the developing thyroid gland and is strongly down-regulated in thyroid carcinomas
G Calì, F Gentile, S Mogavero, P Pallante… - …, 2012 - academic.oup.com
Cadherin (CDH) 16/kidney-specific-cadherin was first described as a kidney-specific
adhesion molecule and thereafter found expressed also in the thyroid gland. We show here …
adhesion molecule and thereafter found expressed also in the thyroid gland. We show here …
[HTML][HTML] PCDH8 is a novel prognostic biomarker in thyroid cancer and promotes cell proliferation and viability
R Yang, N Yang, P Yin, Z Xue, F Sun, R Fan… - Functional & Integrative …, 2024 - Springer
Abstract Protocadherin 8 (PCDH8), a calcium-dependent transmembrane protein in the
protocadherin family, regulates cell adhesion and signal transduction. While some studies …
protocadherin family, regulates cell adhesion and signal transduction. While some studies …
[HTML][HTML] Cadherin 6 is a new RUNX2 target in TGF-β signalling pathway
V Sancisi, G Gandolfi, M Ragazzi, D Nicoli… - PloS one, 2013 - journals.plos.org
Modifications in adhesion molecules profile may change the way tumor cells interact with the
surrounding microenvironment. The Cadherin family is a large group of transmembrane …
surrounding microenvironment. The Cadherin family is a large group of transmembrane …
Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy
M Gugnoni, V Sancisi, G Gandolfi, G Manzotti… - Oncogene, 2017 - nature.com
The transdifferentiation of epithelial cells toward a mesenchymal condition (EMT) is a
complex process that allows tumor cells to migrate to ectopic sites. Cadherins are not just …
complex process that allows tumor cells to migrate to ectopic sites. Cadherins are not just …