NT‐proBNP in heart failure: therapy decisions and monitoring

M Richards, RW Troughton - European journal of heart failure, 2004 - Wiley Online Library
With increasing cardiac dysfunction, a complex neurohormonal response results in
increasing circulating levels of an array of plasma hormones. Increments in plasma levels of …

NT‐proBNP in severe chronic heart failure: rationale, design and preliminary results of the COPERNICUS NT‐proBNP substudy

F Hartmann, M Packer, AJS Coats… - European Journal of …, 2004 - Wiley Online Library
Background: Neither profiles nor prognostic value of cardiac N‐terminal proBNP (NT‐
proBNP) have been prospectively evaluated in a sufficient number of patients with severe …

NT‐proBNP qualifies as a surrogate for clinical end points in heart failure

W Schmitt, H Rühs, R Burghaus… - Clinical …, 2021 - Wiley Online Library
N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) is a well‐established biomarker in
heart failure (HF) but controversially discussed as a potential surrogate marker in HF trials …

[HTML][HTML] Natriuretic peptides in chronic heart failure

HP Brunner-La Rocca, S Sanders-van Wijk - Cardiac failure review, 2019 - ncbi.nlm.nih.gov
Normal brain natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) levels are
helpful in excluding chronic heart failure in the ambulatory setting, although they have been …

The impact of cardiac natriuretic peptide determination on the diagnosis and management of heart failure

J Mair, A Hammerer-Lercher, B Puschendorf - 2001 - degruyter.com
The long-predicted endocrine function of the heart has been proven by the discovery of atrial
natriuretic peptide (atrial natriuretic factor, A-type natriuretic peptide; ANP) 20 years ago …

NT‐proBNP and BNP: biomarkers for heart failure management

P Bettencourt - European journal of heart failure, 2004 - Wiley Online Library
Guidelines for the pharmacological treatment of heart failure (HF) are based on results from
large clinical trials demonstrating benefit. State of the art pharmacological management of …

Comparison of BNP and NT-proBNP in patients with heart failure and reduced ejection fraction

R Rørth, PS Jhund, MB Yilmaz… - Circulation: Heart …, 2020 - Am Heart Assoc
Background: Both BNP (B-type natriuretic peptide) and NT-proBNP (N-terminal pro B-type
natriuretic peptide) are widely used to aid diagnosis, assess the effect of therapy, and predict …

Serial NT-proBNP monitoring and outcomes in outpatients with decompensation of heart failure

A Bayes-Genis, D Pascual-Figal, J Fabregat… - International journal of …, 2007 - Elsevier
BACKGROUND: NT-proBNP is useful for heart failure (HF) diagnosis and prognosis. We
examined the value of serial NT-proBNP monitoring to predict outcomes in decompensated …

A change in N‐terminal pro‐brain natriuretic peptide is predictive of outcome in patients with advanced heart failure

RS Gardner, KS Chong, JJ Morton… - European journal of …, 2007 - Wiley Online Library
Background: The prognosis of chronic heart failure has improved with modern medical
therapy. However, identifying those patients who fail to respond to such therapy and …

Prognostic value of changes in N-terminal pro-brain natriuretic peptide in Val-HeFT (Valsartan Heart Failure Trial)

S Masson, R Latini, IS Anand, S Barlera… - Journal of the American …, 2008 - jacc.org
Objectives: This study sought to evaluate the association between changes over time of N-
terminal pro-brain natriuretic peptide (NT-proBNP) expressed in different ways and outcome …