[HTML][HTML] Role of microRNAs in glioblastoma

M Chen, Z Medarova, A Moore - Oncotarget, 2021 - ncbi.nlm.nih.gov
Glioblastoma is the most common and aggressive primary human brain cancer. MicroRNAs
(miRNAs) are a set of small endogenous non-coding RNA molecules which play critical …

MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics

A Shea, V Harish, Z Afzal, J Chijioke, H Kedir… - Cancer …, 2016 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify …

MicroRNA in human glioma

M Li, J Li, L Liu, W Li, Y Yang, J Yuan - Cancers, 2013 - mdpi.com
Glioma represents a serious health problem worldwide. Despite advances in surgery,
radiotherapy, chemotherapy, and targeting therapy, the disease remains one of the most …

MicroRNA involvement in glioblastoma pathogenesis

J Novakova, O Slaby, R Vyzula, J Michalek - Biochemical and biophysical …, 2009 - Elsevier
MicroRNAs are endogenously expressed regulatory noncoding RNAs. Altered expression
levels of several microRNAs have been observed in glioblastomas. Functions and direct …

Role of microRNAs in gliomagenesis: targeting miRNAs in glioblastoma multiforme therapy

A Nikaki, C Piperi, AG Papavassiliou - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Gliomas consist of a very heterogeneous group of malignant tumors,
accounting for 50–60% of primary brain tumors. Despite all the efforts of cytoreductive …

MicroRNAs in human malignant gliomas

M Mizoguchi, Y Guan, K Yoshimoto, N Hata… - Journal of …, 2012 - Wiley Online Library
MicroRNA (miRNA) is a new class of small noncoding RNA molecules that regulate a wide
spectrum of gene expression in a posttranscriptional manner. MiRNAs play crucial roles in …

Therapeutically significant microRNAs in primary and metastatic brain malignancies

AA Balachandran, LM Larcher, S Chen, RN Veedu - Cancers, 2020 - mdpi.com
Simple Summary The overall survival of brain cancer patients remains grim, with
conventional therapies such as chemotherapy and radiotherapy only providing marginal …

[HTML][HTML] The role of microRNAs in glioma initiation and progression

Y Zhang, A Dutta, R Abounader - Frontiers in bioscience: a journal …, 2012 - ncbi.nlm.nih.gov
Abstract micoRNAs (miRNAs) are small noncoding RNAs that regulate gene expression by
targeting the mRNAs of a large number of human genes. Gliomas are the most common and …

MicroRNA-based drugs for brain tumors

S Anthiya, A Griveau, C Loussouarn, P Baril, M Garnett… - Trends in cancer, 2018 - cell.com
MicroRNAs (miRNAs) are key regulatory elements encoded by the genome. A single miRNA
can downregulate the expression of multiple genes involved in diverse functions. Because …

Roles of microRNAs during glioma tumorigenesis and progression

S Wang, Y Yin, S Liu - 2019 - digitum.um.es
Glioma is the most common and aggressive type of brain tumor. It has a poor prognosis and
a high recurrence rate. Despite continued advances in surgery, chemotherapy and …