Neural tube defects (NTDs), a set of structural abnormalities affecting the brain, spinal cord,
and the skeletal and connective tissues that protect them, are common malformations …

Epidemiological analysis of multiâ•’site closure failure of neural tube in humans Page 1
American Journal of Medical Genetics 66:64-68 (1996) Epidemiological Analysis of Multi-Site …

Evidence is presented to support the recent suggestion that human neural tube closure is
similar to that observed in mice, and comprises several regionally distinct closure sites …

Birth defects (congenital anomalies) are the leading cause of death in babies under 1 year
of age. Neural tube defects (NTD), with a birth incidence of approximately 1/1000 in …

Although neural tube defects are a common congenital anomaly, their etiology is not known.
Human studies have emphasized the pathology and epidemiology of the defects and …

While neural tube defects (NTD) overall have a female sex bias, this does not apply to all
sites along the neuraxis. The findings regarding sex and NTD in a series of midtrimester …

Congenital defects of neural tube closure (neural tube defects; NTDs) are among the
commonest and most severe disorders of the fetus and newborn. Disturbance of any of the …

During embryonic development, the central nervous system forms as the neural plate and
then rolls into a tube in a complex morphogenetic process known as neurulation. Neural …

The search for genetic determinants of human neural tube def... : Current Opinion in
Pediatrics The search for genetic determinants of human neural tube defects : Current …

We present evidence for multisite NT closure in humans with representative examples of
types of NTDs that would be expected if NT closure in humans is similar to experimental …