[HTML][HTML] Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy

L Poillet-Perez, G Despouy, R Delage-Mourroux… - Redox biology, 2015 - Elsevier
Cancer formation is a complex and highly regulated multi-step process which is highly
dependent of its environment, from the tissue to the patient. This complexity implies the …

Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment

MB Azad, Y Chen, SB Gibson - Antioxidants & redox signaling, 2009 - liebertpub.com
Reactive oxygen species (ROS) have been identified as signaling molecules in various
pathways regulating both cell survival and cell death. Autophagy, a self-digestion process …

ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy

M Dewaele, H Maes, P Agostinis - Autophagy, 2010 - Taylor & Francis
Mounting evidence suggests that reactive oxygen species (ROS) are multifaceted signalling
molecules implicated in a variety of cellular programs during physiological as well as …

[HTML][HTML] Crosstalk between ROS and autophagy in tumorigenesis: understanding the multifaceted paradox

A Hasan, SF Rizvi, S Parveen, N Pathak, A Nazir… - Frontiers in …, 2022 - frontiersin.org
Cancer formation is a highly regulated and complex process, largely dependent on its
microenvironment. This complexity highlights the need for developing novel target-based …

Redox balance and autophagy regulation in cancer progression and their therapeutic perspective

SU Khan, K Fatima, S Aisha, B Hamza, F Malik - Medical Oncology, 2022 - Springer
Cellular ROS production participates in various cellular functions but its accumulation
decides the cell fate. Malignant cells have higher levels of ROS and active antioxidant …

Reactive oxygen species regulation of autophagy in cancer: implications for cancer treatment

L Li, G Ishdorj, SB Gibson - Free Radical Biology and Medicine, 2012 - Elsevier
Reactive oxygen species (ROS) are important in regulating normal cellular processes, but
deregulated ROS contribute to the development of various human diseases including …

A matter of balance between life and death: targeting reactive oxygen species (ROS)-induced autophagy for cancer therapy

SB Gibson - Autophagy, 2010 - Taylor & Francis
Reactive oxygen species (ROS) have been implicated in many biological functions and
diseases. Often their role is counterintuitive, where ROS can either promote cell survival or …

Targeting ROS-mediated crosstalk between autophagy and apoptosis in cancer

L Gao, J Loveless, C Shay, Y Teng - Reviews on new drug targets in age …, 2020 - Springer
The control of crosstalk between autophagy and apoptosis in tumor cells can remove a
critical barrier to comprehensive and efficacious treatment for cancer. Reactive oxygen …

[HTML][HTML] The interplay between autophagy and ROS in tumorigenesis

S Kongara, V Karantza - Frontiers in oncology, 2012 - frontiersin.org
Reactive oxygen species (ROS) at physiological levels are important cell signaling
molecules. However, aberrantly high ROS are intimately associated with disease and …

Redox signaling: Potential arbitrator of autophagy and apoptosis in therapeutic response

L Zhang, K Wang, Y Lei, Q Li, EC Nice… - Free Radical Biology and …, 2015 - Elsevier
Redox signaling plays important roles in the regulation of cell death and survival in
response to cancer therapy. Autophagy and apoptosis are discrete cellular processes …