Statistical evaluation of test-retest studies in PET brain imaging
Background Positron emission tomography (PET) is a molecular imaging technology that
enables in vivo quantification of metabolic activity or receptor density, among other …
enables in vivo quantification of metabolic activity or receptor density, among other …
Drug development in Alzheimer's disease: the contribution of PET and SPECT
LD Declercq, R Vandenberghe, K Van Laere… - Frontiers in …, 2016 - frontiersin.org
Clinical trials aiming to develop disease-altering drugs for Alzheimer's disease (AD), a
neurodegenerative disorder with devastating consequences, are failing at an alarming rate …
neurodegenerative disorder with devastating consequences, are failing at an alarming rate …
An overview of PET neuroimaging
I Nasrallah, J Dubroff - Seminars in nuclear medicine, 2013 - Elsevier
Over the past 35 years or so, PET brain imaging has allowed powerful and unique insights
into brain function under normal conditions and in disease states. Initially, as PET …
into brain function under normal conditions and in disease states. Initially, as PET …
[PDF][PDF] PET and drug research and development
The use of PET to examine the behavioral, therapeutic and toxic properties of drugs and
substances of abuse is emerging as a powerful new scientific tool. PET provides a new …
substances of abuse is emerging as a powerful new scientific tool. PET provides a new …
Quantification of SPECT and PET for drug development
Y Seo - Current radiopharmaceuticals, 2008 - ingentaconnect.com
Development of a new drug faces multi-faceted sequences in the pipeline. Once a drug
candidate is identified, evaluation process can be accelerated by in vivo noninvasive …
candidate is identified, evaluation process can be accelerated by in vivo noninvasive …
Molecular imaging with PET
SM Ametamey, M Honer, PA Schubiger - Chemical reviews, 2008 - ACS Publications
Recent advances in noninvasive imaging modalities have opened endless opportunities for
molecular diagnostic and therapeutic procedures. The term “molecular imaging” is broadly …
molecular diagnostic and therapeutic procedures. The term “molecular imaging” is broadly …
Strategies for designing novel positron emission tomography (PET) radiotracers to cross the blood–brain barrier
Positron emission tomography (PET) is a powerful tool for imaging biological processes in
the central nervous system (CNS). Designing PET radiotracers capable of crossing the …
the central nervous system (CNS). Designing PET radiotracers capable of crossing the …
Is there a role for GPCR agonist radiotracers in PET neuroimaging?
Positron emission tomography (PET) is a molecular imaging modality that enables in vivo
exploration of metabolic processes and especially the pharmacology of neuroreceptors. G …
exploration of metabolic processes and especially the pharmacology of neuroreceptors. G …
PET and SPECT imaging of the brain: history, technical considerations, applications, and radiotracers
KM Davis, JL Ryan, VD Aaron, JB Sims - Seminars in Ultrasound, CT and …, 2020 - Elsevier
Advances in nuclear medicine have revolutionized our ability to accurately diagnose
patients with a wide array of neurologic pathologies and provide appropriate therapy. The …
patients with a wide array of neurologic pathologies and provide appropriate therapy. The …
Unique roles of SPET brain imaging in clinical and research studies: Lessons from Parkinson's disease research
J Seibyl, D Jennings, R Tabamo… - The Quarterly Journal of …, 2005 - search.proquest.com
The increasing availability of PET imaging in nuclear medicine expands the armamentarium
of clinical and research tools for improving diagnosis and treatment of neuropsychiatric …
of clinical and research tools for improving diagnosis and treatment of neuropsychiatric …