As in most bacteria, topological problems arising from the circularity of the two Vibrio
cholerae chromosomes, chrI and chrII, are resolved by the addition of a crossover at a …

The circular chromosomes of bacteria can be concatenated into dimers by homologous
recombination. Dimers are solved by the addition of a cross-over at a specific chromosomal …

A major determinant of Vibrio cholerae pathogenicity, the cholera enterotoxin, is encoded in
the genome of an integrated phage, CTXϕ. CTXϕ integration depends on two host-encoded …

The chromosome dimer resolution machinery of bacteria is generally composed of two
tyrosine recombinases, XerC and XerD. They resolve chromosome dimers by adding a …

CTXφ is a filamentous bacteriophage that encodes cholera toxin and integrates site‐
specifically into the larger of the two Vibrio cholerae chromosomes. The CTXφ genome lacks …

Cholera toxin is encoded in the genome of CTXφ, a lysogenic filamentous phage of Vibrio
cholerae. CTXφ variants contribute to the genetic diversity of cholera epidemic strains. It has …

Toxigenic conversion of Vibrio cholerae bacteria results from the integration of a filamentous
phage, CTXφ. Integration is driven by the bacterial Xer recombinases, which catalyse the …

ABSTRACT CTXΦ, a filamentous vibriophage encoding cholera toxin, uses a unique
strategy for its lysogeny. The single-stranded phage genome forms intramolecular base …

Unlike most bacteria, Vibrio cholerae harbors two distinct, nonhomologous circular
chromosomes (chromosome I and II). Many features of chromosome II are plasmid-like …

The seventh cholera pandemic emerged in the poorer nations of the world towards the end
of the 20th century and continues to kill thousands of people per year. The causative agent …