Background Neuroinflammation and apoptosis are involved in the pathogenesis of
ischaemic stroke. Alisol A 24-acetate (24A) exerts a strong inhibitory effect on inflammation …

Objective Tissue injury and inflammation are two potential outcomes of cerebral ischemia–
reperfusion (I/R) injury. Salvianolic acid B (Sal B), isolated from the roots of Salvia …

Cerebral ischemia is among the leading causes of death and long‑term disability worldwide.
The aim of the present study was to investigate the effects of aloperine (ALO) on cerebral …

Alisol A, a triterpene isolated from Alisma Orientale, has been shown to exhibit anti-
inflammatory effects and vascular protection. This study was designed to observe the effect …

6′‐O‐galloylpaeoniflorin (GPF), a galloylated derivative of paeoniflorin isolated from peony
root, has been proven to possess antioxidant potential. In this present study, we revealed …

The present study was designed to investigate the protective effect of eriodictyol on MCAO-
induced brain injury and its regulation of neural function and to explore the mechanism of its …

Alpha-asarone, a major active component isolated from Acorus gramineus, can affect brain
functions and behaviors by multiple mechanisms. However, the effect of alpha-asarone on …

Fracture in acute stage of ischemic stroke can increase inflammatory response and enhance
stroke injury. Loganin alleviates the symptoms of many inflammatory diseases through its …

Background Excitatory amino acid toxicity, oxidative stress, intracellular calcium overload, as
well as inflammation and apoptosis are involved in the pathological process after cerebral …

Background Neuroinflammation plays a pivotal role in the acute progression of cerebral
ischemia/reperfusion injury (I/RI). We previously reported that genistein-3′-sodium …