In recent years, split inteins have seen widespread use as molecular platforms for the design
of a variety of peptide and protein chemistry technologies, most notably protein ligation. The …

Protein splicing in trans by split inteins has increasingly become a powerful protein-
engineering tool for protein ligation, both in vivo and in vitro. Over 100 naturally occurring …

Split inteins associate to trigger protein splicing in trans, a post-translational modification in
which protein sequences fused to the intein pair are ligated together in a traceless manner …

Protein trans-splicing (PTS) by split inteins has found widespread use in chemical biology
and biotechnology. Herein, we describe the use of a consensus design approach to …

Over the past decade split inteins have established themselves as powerful tools for protein
engineering, protein semisynthesis, and protein functional control approaches. Their key …

Inteins are protein segments capable of joining adjacent residues via a peptide bond. In this
process known as protein splicing, the intein itself is not present in the final sequence, thus …

Split-protein systems are invaluable tools used for the discovery and investigations of the
complexities of protein functions and interactions. Split-protein systems rely on the non …

The split inteins from the DnaE cyanobacterial family are efficient and versatile tools for
protein engineering and chemical biology applications. Their ultrafast splicing kinetics allow …

Inteins are protein segments that are capable of enabling the ligation of flanking extein into a
new protein, a process known as protein splicing. Since its discovery, inteins have become …

Inteins excise themselves out of precursor proteins by the protein splicing reaction and have
emerged as valuable protein engineering tools in numerous and diverse biotechnological …