Split inteins carry out a naturally occurring process known as protein trans‐splicing, where
two protein fragments bind to form a catalytically competent enzyme, then catalyze their own …

Protein trans-splicing by split inteins has many uses in protein production and research.
Splicing proteins with synthetic peptides, which employs atypical split inteins, is particularly …

Protein splicing is an autocatalytic process involving self-excision of an internal protein
domain, the intein, and concomitant ligation of the two flanking sequences, the exteins, with …

Split inteins are a class of naturally occurring proteins that carry out protein splicing in trans.
The chemical mechanism of protein trans-splicing is well-understood and has been …

Inteins are proteins that excise themselves out of host proteins and ligate the flanking
polypeptides in an auto-catalytic process called protein splicing. They are gaining …

Protein splicing domains, also called inteins, have become a powerful biotechnological tool
for applications involving molecular biology and protein engineering. Early applications of …

Split intein-mediated protein trans-splicing (PTS) is widely applied in chemical biology and
biotechnology to carry out traceless and specific protein ligation. However, the external …

Split-inteins are a subset of inteins that are expressed in two separate halves and catalyze
splicing in trans upon association of the two domains. They occur naturally and have also …

Inteins are auto-processing domains found in organisms from all domains of life. These
proteins carry out a process known as protein splicing, which is a multi-step biochemical …

The site-selective introduction of synthetic moieties into proteins is a highly important and
long-standing goal in many areas of biotechnology, biomedicine, and basic research. The …