Maternal flaxseed diet during pregnancy or lactation increases female rat offspring's susceptibility to carcinogen-induced mammary tumorigenesis
G Khan, P Penttinen, A Cabanes, A Foxworth… - Reproductive …, 2007 - Elsevier
Flaxseed contains several dietary components that have been linked to low breast cancer
risk; ie, n-3 polyunsaturated fatty acids (PUFAs), lignans and fiber, but it also contains …
risk; ie, n-3 polyunsaturated fatty acids (PUFAs), lignans and fiber, but it also contains …
Exposure to flaxseed or its lignan component during different developmental stages influences rat mammary gland structures
JCL Tou, LU Thompson - Carcinogenesis, 1999 - academic.oup.com
Reduction of the highly proliferative terminal end bud (TEB) structures in the developing
mammary gland by differentiation to alveolar buds (ABs) and lobules has been suggested to …
mammary gland by differentiation to alveolar buds (ABs) and lobules has been suggested to …
Exposure to flaxseed or its purified lignan during suckling inhibits chemically induced rat mammary tumorigenesis
Previous studies have shown that feeding flaxseed (FS) or its lignan secoisolariciresinol
diglucoside (SDG) to rat dams during lactation enhances the differentiation of rat mammary …
diglucoside (SDG) to rat dams during lactation enhances the differentiation of rat mammary …
Maternal dietary exposure to fiber during pregnancy and mammary tumorigenesis among rat offspring
B Yu, G Khan, A Foxworth, K Huang… - … journal of cancer, 2006 - Wiley Online Library
Maternal diet during pregnancy has been proposed to modify female offspring's later
susceptibility to develop breast cancer; however, most of the dietary factors identified thus far …
susceptibility to develop breast cancer; however, most of the dietary factors identified thus far …
Exposure to flaxseed or purified lignan during lactation influences rat mammary gland structures
WE Ward, FO Jiang, LU Thompson - Nutrition and cancer, 2000 - Taylor & Francis
Previous investigation demonstrated that feeding a 10% flaxseed (10F) diet during
pregnancy and lactation enhanced the differentiation of highly proliferative terminal end bud …
pregnancy and lactation enhanced the differentiation of highly proliferative terminal end bud …
[HTML][HTML] Interactive effects of Flax seeds and tamoxifen on human breast cancer
LU Thompson, J Chen, E Hui… - Proc 60th Flax Institute …, 2004 - goldenvalleyflax.com
Flaxseed is the richest source of the phytoestrogen lignans, containing 75-800 times higher
concentration than other plant foods in the vegetarian diet. It is also a very rich source of a …
concentration than other plant foods in the vegetarian diet. It is also a very rich source of a …
Dietary modulation of pregnancy estrogen levels and breast cancer risk among female rat offspring
L Hilakivi-Clarke, E Cho, A Cabanes, S DeAssis… - Clinical cancer …, 2002 - AACR
Purpose: Against the hypothesis that high estrogen levels in utero increase the risk of
developing breast cancer in later life are data showing that pregnancy estrogen levels are …
developing breast cancer in later life are data showing that pregnancy estrogen levels are …
Consumption of flaxseed, a rich source of lignans, is associated with reduced breast cancer risk
EC Lowcock, M Cotterchio, BA Boucher - Cancer Causes & Control, 2013 - Springer
Purpose To investigate the association between intake of flaxseed—the richest source of
dietary lignans (a class of phytoestrogens)—and breast cancer risk. Methods A food …
dietary lignans (a class of phytoestrogens)—and breast cancer risk. Methods A food …
Mammary gland morphogenesis is enhanced by exposure to flaxseed or its major lignan during suckling in rats
The exposure of rats to 10% flaxseed (FS) or an equivalent level of its major lignan,
secoisolariciresinol diglucoside (SDG), during suckling enhances mammary gland …
secoisolariciresinol diglucoside (SDG), during suckling enhances mammary gland …
Effect of flaxseed consumption on urinary levels of estrogen metabolites in postmenopausal women
SR Sturgeon, SL Volpe, E Puleo… - Nutrition and …, 2010 - Taylor & Francis
Flaxseed is a rich source of dietary lignans. It has been hypothesized that lignans may
decrease breast cancer risk through modulation of endogenous hormone levels. The aim of …
decrease breast cancer risk through modulation of endogenous hormone levels. The aim of …
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- lactation influences gland structures
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- estrogen metabolites postmenopausal women
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- pregnancy or lactation mammary tumorigenesis
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- dietary modulation rat offspring