Human T-Cell Leukemia Virus Type 1 Envelope Protein: Post-Entry Roles in Viral Pathogenesis

V Maksimova, AR Panfil - Viruses, 2022 - mdpi.com
Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus that is the causative
infectious agent of adult T-cell leukemia/lymphoma (ATL), an aggressive and fatal CD4+ T …

Molecular biology of human T cell leukemia virus

L Ratner - Seminars in diagnostic pathology, 2020 - Elsevier
Human T cell leukemia virus type 1 (HTLV-1) is a horizontally transmitted virus infection of
CD4+ lymphocytes which causes adult T cell leukemia-lymphoma (ATLL) and HTLV …

Human T-cell leukemia virus type 1: replication, proliferation and propagation by Tax and HTLV-1 bZIP factor

M Matsuoka, J Yasunaga - Current opinion in virology, 2013 - Elsevier
Highlights•HTLV-1 primarily transmits by cell-to-cell contact.•HTLV-1 increases the number
of infected cells by clonal proliferation to facilitate its transmission.•HTLV-1 bZIP factor (HBZ) …

Human T-cell leukemia virus type 2 post-transcriptional control protein p28 is required for viral infectivity and persistence in vivo

B Yamamoto, M Li, M Kesic, I Younis, MD Lairmore… - Retrovirology, 2008 - Springer
Background Human T-cell leukemia virus (HTLV) type 1 and type 2 are related but distinct
pathogenic complex retroviruses. HTLV-1 is associated with adult T-cell leukemia and a …

Human T-cell lymphotropic virus type 1 Tax mediates enhanced transcription in CD4+ T lymphocytes

GC Newbound, JM Andrews, JP O'Rourke… - Journal of …, 1996 - Am Soc Microbiol
Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell
leukemia/lymphoma and is associated with a variety of immunoregulatory disorders. HTLV-1 …

HTLV-1 HBZ viral protein: a key player in HTLV-1 mediated diseases

M Baratella, G Forlani, RS Accolla - Frontiers in microbiology, 2017 - frontiersin.org
Human T cell leukemia virus type 1 (HTLV-1) is an oncogenic human retrovirus that has
infected 10–15 million people worldwide. After a long latency, 3–5% of infected individuals …

Human T-cell leukemia virus type 1 pX-I and pX-II open reading frames are dispensable for the immortalization of primary lymphocytes

MD Robek, FH Wong, L Ratner - Journal of virology, 1998 - Am Soc Microbiol
Human T-cell leukemia virus type 1 (HTLV-1) infects and transforms CD4+ T-lymphocytes
both in vivo and in vitro. Although the Tax protein of HTLV-1 has been strongly implicated as …

Human T-cell leukemia virus type 1 (HTLV-1) Tax1 oncoprotein but not HTLV-2 Tax2 induces the expression of OX40 ligand by interacting with p52/p100 and RelB

Y Motai, M Takahashi, T Takachi, M Higuchi, T Hara… - Virus Genes, 2016 - Springer
Human T-cell leukemia virus type 1 (HTLV-1) is a human retrovirus associated with the
development of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical …

Human T-Cell Leukemia Virus Type 1 Oncogenesis between Active Expression and Latency: A Possible Source for the Development of Therapeutic Targets

F Marino-Merlo, S Grelli, A Mastino, M Lai… - International Journal of …, 2023 - mdpi.com
The human T-cell leukemia virus type 1 (HTLV-1) is the only known human oncogenic
retrovirus. HTLV-1 can cause a type of cancer called adult T-cell leukemia/lymphoma (ATL) …

HTLV-1 Rex is required for viral spread and persistence in vivo but is dispensable for cellular immortalization in vitro

J Ye, L Silverman, MD Lairmore, PL Green - Blood, 2003 - ashpublications.org
Human T-cell leukemia virus type 1 (HTLV-1) is a pathogenic retrovirus associated with
adult T-cell leukemia (ATL) and a variety of immune-mediated disorders including the …