The vascular system is essential for embryogenesis, healing, and homeostasis. Dysfunction
or deregulated blood vessel function contributes to multiple diseases, including diabetic …

Physiological angiogenesis refers to a naturally occurring process of blood vessel growth
and regression, and it occurs as an integral component of tissue repair and regeneration …

Engineered blood vessels have often been found to be immature and unstable. Similarly,
numerous pathologies such as diabetic retinopathy and cancer are characterized by highly …

The vasculature of an organism has the daunting task of connecting all the organ systems to
nourish tissue and sustain life. This complex network of vessels and associated cells must …

From developmental stages until adulthood, the circulatory system remodels in response to
changes in blood flow in order to maintain vascular homeostasis. Remodeling processes …

The blood vasculature is an organ pervading all other organs (almost). During vascular
development, cell–cell signaling by extracellular ligands and cell surface receptors ensure …

The regression of blood vessels is an intrinsic feature of both physiological and pathological
processes. This suggests the existence of molecular regulators of regression, which would …

Therapeutic modulation of vascular cell proliferation and migration is essential for the
effective inhibition of angiogenesis in cancer or its induction in cardiovascular disease. The …

The vascular system is a hierarchically organized network of blood vessels that play crucial
roles in embryogenesis, homeostasis and disease. Blood vessels are built by endothelial …

In multicellular organisms, angiogenesis, the formation of new blood vessels from pre-
existing ones, is an essential process for growth and development. Different mechanisms …