Identification of the central tachykinin receptor subclass involved in substance P-induced cardiovascular and behavioral responses in conscious rats
K Ito, C Tschöpe, N Jost, J Culman, C Lebrun… - European journal of …, 1992 - Elsevier
To identify the tachykinin receptor subclass involved in the central cardiovascular and
behavioral actions of substance P (SP), we compared the central actions of SP with those of …
behavioral actions of substance P (SP), we compared the central actions of SP with those of …
Effects of the tachykinin NK1 receptor antagonist, RP 67580, on central cardiovascular and behavioural effects of substance P, neurokinin A and neurokinin B
J Culman, B Wiegand, H Spitznagel… - British journal of …, 1995 - Wiley Online Library
1 We have investigated the effects of the non‐peptide NK1 tachykinin receptor antagonist,
RP 67580, and its inactive enantiomer, RP 68651, on the cardiovascular and behavioural …
RP 67580, and its inactive enantiomer, RP 68651, on the cardiovascular and behavioural …
Substance P and neurokinin A induced desentization to cardiovascular and behavioral effects: evidence for the involvement of different tachykinin receptors
Desensitization and cross-desensitization to the cardiovascular and behavioral effects
elicited by intracerebroventricular (icv) substance P (SP) and neurokinin A (NKA) injections …
elicited by intracerebroventricular (icv) substance P (SP) and neurokinin A (NKA) injections …
Effect of tachykinin receptor inhibition in the brain on cardiovascular and behavioral responses to stress
J Culman, S Klee, C Ohlendorf, T Unger - Journal of Pharmacology and …, 1997 - ASPET
The neurokinins, substance P (SP) and neurokinin A (NKA) represent natural, nonspecific
ligands of NK1 and NK2receptors. In our study in conscious rats, we tested the hypothesis …
ligands of NK1 and NK2receptors. In our study in conscious rats, we tested the hypothesis …
Cardiovascular and behavioural effects of centrally administered tachykinins in the rat: characterization of receptors with selective antagonists
P Picard, D Regoli, R Couture - British journal of pharmacology, 1994 - Wiley Online Library
1 The effects of intracerebroventricular (icv) injection of selective and potent NK1 (RP
67580), NK2 (SR 48968) and NK3 (R 486,[Trp7, β‐Ala8] NKA (4–10)) receptor antagonists …
67580), NK2 (SR 48968) and NK3 (R 486,[Trp7, β‐Ala8] NKA (4–10)) receptor antagonists …
Use of selective antagonists to dissociate the central cardiovascular and behavioural effects of tachykinins on NK1 and NK2 receptors in the rat.
The effects of intracerebroventricular (icv) pretreatment with selective NK1 ((+/-)-CP 96,345),
NK2a (MEN 10,207; MEN 10,376) and NK2b (R 396) tachykinin receptor antagonists on the …
NK2a (MEN 10,207; MEN 10,376) and NK2b (R 396) tachykinin receptor antagonists on the …
Hypotensive effect of intravenous injection of tachykinins in conscious, freely moving spontaneously hypertensive and Wistar Kyoto rats
P Pompei, SJ Tayebati, C Polidori, M Perfumi… - Peptides, 1993 - Elsevier
The present study evaluated the sensitivity of spontaneously hypertensive (SHR) and of
Wistar Kyoto (WKY) rats to the hypotensive effect of tachykinins (TKs). Eledoisin, substance …
Wistar Kyoto (WKY) rats to the hypotensive effect of tachykinins (TKs). Eledoisin, substance …
Central cardiovascular and behavioral effects of carboxy-and amino-terminal fragments of substance P in conscious rats
The central cardiovascular and behavioral effects of carboxy-(SP 5–11, SP 6–11, SP 7–11,
SP 8–11) and amino-(SP 1–7, SP 1–9) terminal substance P (SP) fragments were compared …
SP 8–11) and amino-(SP 1–7, SP 1–9) terminal substance P (SP) fragments were compared …
Comparative distribution and cardiovascular actions of substance P and substance K within the nucleus tractus solitarius of rats
DA Carter, SL Lightman - Neuropeptides, 1986 - Elsevier
An investigation has been made into the comparative distribution and cardiovascular actions
of Substance P (SP) and Substance K (SK) in the nucleus tractus solitarius (NTS) of rats. The …
of Substance P (SP) and Substance K (SK) in the nucleus tractus solitarius (NTS) of rats. The …
Characterization of the peripheral action of neurokinins and neurokinin receptor selective agonists on the rat cardiovascular system
R Couture, O Laneuville, C Guimond… - Naunyn-Schmiedeberg's …, 1989 - Springer
The effects on mean arterial pressure (MAP) and heart rate (HR) of increasing doses (0.65–
65 nmol/kg) of substance P (SP), neurokinin A (NKA), neurokinin B (NKB) and selective …
65 nmol/kg) of substance P (SP), neurokinin A (NKA), neurokinin B (NKB) and selective …
相关搜索
- cardiovascular and behavioral responses
- conscious rats behavioral responses
- evidence for the involvement tachykinin receptors
- conscious rats amino terminal
- central cardiovascular selective antagonists
- central cardiovascular behavioural effects
- tachykinin nk1 receptor antagonist
- tachykinins on nk1 and nk2 receptors
- peripheral action neurokinin receptor
- anaesthetized rat peripheral effects
- intravenous injection hypotensive effect
- wistar kyoto hypotensive effect
- behavioural effects selective antagonists
- central cardiovascular receptors in the rat
- receptors in the rat selective antagonists
- characterization of receptors selective antagonists