Prevention or treatment of ARDS with aspirin: a review of preclinical models and meta-analysis of clinical studies

BA Panka, HJ de Grooth, AME Spoelstra-de Man… - Shock, 2017 - journals.lww.com
Background: The acute respiratory distress syndrome (ARDS) is a life-threating disorder that
contributes significantly to critical illness. No specific pharmacological interventions directed …

Aspirin use and long-term rates of sepsis: A population-based cohort study

J Hsu, JP Donnelly, NS Chaudhary, JX Moore… - PLoS …, 2018 - journals.plos.org
Objective Sepsis is the syndrome of life-threatening organ dysfunction resulting from
dysregulated host response to infection. Aspirin, an anti-inflammatory agent, may play a role …

Prehospital statin and aspirin use and the prevalence of severe sepsis and acute lung injury/acute respiratory distress syndrome

HR O'Neal Jr, T Koyama, EAS Koehler… - Critical care …, 2011 - journals.lww.com
Objectives: To determine whether prehospital statin use is associated with a lower risk of
sepsis, acute lung injury/acute respiratory distress syndrome, and mortality in critically ill …

[HTML][HTML] Prehospital NSAIDs use prolong hospitalization in patients with pleuro-pulmonary infection

OS Kotsiou, SG Zarogiannis, KI Gourgoulianis - Respiratory Medicine, 2017 - Elsevier
Objective Nonsteroidal anti-inflammatory drug (NSAID) pre-hospitalization consumption
might affect the course of pneumonia. We opted to assess the potential effects of pre …

Early and pre-discharge aspirin administration among patients with acute myocardial infarction: current clinical practice and trends in the United States

RC Becker, M Burns, JM Gore, C Lambrew… - Journal of thrombosis …, 2000 - Springer
Objectives: The purpose of our study was to determine the frequency of aspirin
administration among patients with acute myocardial infarction (MI) as dictated by …

Prehospital aspirin administration for acute coronary syndrome (ACS) in the USA: an EMS quality assessment using the NEMSIS 2011 database

KL Tataris, MP Mercer, P Govindarajan - Emergency Medicine Journal, 2015 - emj.bmj.com
Introduction National practice guidelines recommend early aspirin administration to reduce
mortality in acute coronary syndrome (ACS). Although timely administration of aspirin has …

Changes over time in the use of aspirin in patients hospitalized with acute myocardial infarction (1975 to 1997): a population-based perspective

EA Jackson, R Sivasubramian, FA Spencer… - American heart …, 2002 - Elsevier
Objective The purpose of this study was to examine 2 decade-long trends in the use of
aspirin and associated outcomes in patients hospitalized with acute myocardial infarction …

Effects of antiplatelet therapy on the mortality rate of patients with sepsis: a meta-analysis

Y Ouyang, Y Wang, B Liu, X Ma, R Ding - Journal of critical care, 2019 - Elsevier
Purpose Abnormal platelet activation plays an important role in the development of sepsis.
The effect of antiplatelet drugs on the outcome of patients with sepsis remains unclear. This …

Too little aspirin for secondary prevention after acute myocardial infarction in patients at high risk for cardiovascular events: results from the MITRA study

B Frilling, R Schiele, AK Gitt, R Zahn, S Schneider… - American heart …, 2004 - Elsevier
BACKGROUND: A meta-analysis of randomized trials has shown a significant reduction of
mortality rate in patients receiving aspirin for secondary prevention after acute myocardial …

Hemorrhagic complications associated with aspirin: an underestimated hazard in clinical practice?

JM Siller-Matula - Jama, 2012 - jamanetwork.com
ASPIRIN IS WIDELY USED FOR PRIMARY AND SECOND-ary prevention of cardiovascular
events. Substan-tial scientific evidence supports the beneficial role of aspirin in reducing the …