Extracellular signal-regulated kinase-2, but not c-Jun NH2-terminal kinase, activation correlates with surface IgM-mediated apoptosis in the WEHI 231 B cell line
JR Lee, GA Koretzky - The Journal of Immunology, 1998 - journals.aai.org
Both extracellular signal-regulated kinase (ERK) and c-Jun NH 2-terminal kinase (JNK)
have been implicated in mediating the signaling events that precede apoptosis. We studied …
have been implicated in mediating the signaling events that precede apoptosis. We studied …
Role of mitogen‐activated protein kinases in activation‐induced apoptosis of T cells
ZHU, AKATSUKA, COOPER, ANASETTI - Immunology, 1999 - Wiley Online Library
A member of the mitogen‐activated protein (MAP) kinase family, Jun N‐terminal kinase
(JNK), has been implicated in regulating apoptosis in various cell types. We have …
(JNK), has been implicated in regulating apoptosis in various cell types. We have …
Prevention of anti-IgM-induced apoptosis accompanying G1 arrest in B lymphoma cells overexpressing dominant-negative mutant form of c-Jun N-terminal kinase 1
E Takada, H Toyota, J Suzuki… - The Journal of …, 2001 - journals.aai.org
A family of mitogen-activated protein (MAP) kinases comprising the extracellular signal-
regulated kinases (ERKs), c-Jun N-terminal kinases (JNKs), and p38 MAP kinases are …
regulated kinases (ERKs), c-Jun N-terminal kinases (JNKs), and p38 MAP kinases are …
Activation of mitogen‐activated protein kinases via CD40 is distinct from that stimulated by surface IgM on B cells
M Kashiwada, Y Kaneko, H Yagita… - European journal of …, 1996 - Wiley Online Library
CD40 plays critical roles in B cell proliferation and differentiation in response to T cell‐
dependent antigenic stimulation. It has been suggested that CD40‐mediated biological …
dependent antigenic stimulation. It has been suggested that CD40‐mediated biological …
Differential activation and regulation of mitogen‐activated protein kinases through the antigen receptor and CD40 in human B cells
In human B cells, antigen receptor ligation and CD40 ligation are known to activate the
extracellular‐regulated kinases (ERK) and c‐Jun N‐terminal kinase (JNK) pathways, which …
extracellular‐regulated kinases (ERK) and c‐Jun N‐terminal kinase (JNK) pathways, which …
Differential coupling of membrane Ig and CD40 to the extracellularly regulated kinase signaling pathway
JM Purkerson, DC Parker - The Journal of Immunology, 1998 - journals.aai.org
Coupling of membrane Ig (mIg) and CD40 to the extracellularly regulated kinase (ERK)
signal transduction pathway was examined in the WEHI-231 B lymphoma and normal …
signal transduction pathway was examined in the WEHI-231 B lymphoma and normal …
Differential role of p38 and c-Jun N-terminal kinase 1 mitogen-activated protein kinases in NK cell cytotoxicity
R Trotta, K Fettucciari, L Azzoni, B Abebe… - The Journal of …, 2000 - journals.aai.org
The serine-threonine mitogen-activated protein kinase (MAPK) family includes extracellular
signal-regulated kinases (ERK), c-Jun N-terminal kinases (JNK), and p38 kinases. In NK …
signal-regulated kinases (ERK), c-Jun N-terminal kinases (JNK), and p38 kinases. In NK …
Inhibition of mitogen-activated protein kinase kinase blocks T cell proliferation but does not induce or prevent anergy
DR DeSilva, EA Jones, MF Favata… - The Journal of …, 1998 - journals.aai.org
Three mitogen-activated protein kinase pathways are up-regulated during the activation of T
lymphocytes, the extracellular signal-regulated kinase (ERK), Jun NH 2-terminal kinase, and …
lymphocytes, the extracellular signal-regulated kinase (ERK), Jun NH 2-terminal kinase, and …
Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor.
CL Sutherland, AW Heath, SL Pelech… - … (Baltimore, Md.: 1950 …, 1996 - journals.aai.org
B cell antigen receptor (BCR)-induced apoptosis in the WEHI-231 B lymphoma cell line can
be prevented by engaging CD40. We have used this cell line to investigate the role of …
be prevented by engaging CD40. We have used this cell line to investigate the role of …
The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression
M Faris, N Kokot, K Latinis, S Kasibhatla… - The Journal of …, 1998 - journals.aai.org
T lymphocytes undergo apoptosis in response to cellular stress, including UV exposure and
gamma irradiation. However, the mechanism by which stress stimuli induce apoptosis is not …
gamma irradiation. However, the mechanism by which stress stimuli induce apoptosis is not …