Autism is a particularly complex disorder when considered from virtually any methodological
framework, including the perspective of human genetics. We first present a review of the …

Autism is a heritable disorder characterized by phenotypic and genetic complexity. This
review begins by surveying current linkage, gene association, and cytogenetic studies …

Autism is a neurodevelopmental disorder with high heritability and a likely complex genetic
architecture. Much genetic evidence has accumulated in the last 20 years but no gene has …

Autism is characterized by impairments in reciprocal social interaction and communication,
and restricted and stereotyped patterns of interests and activities. Developmental difficulties …

Autism spectrum disorder (ASD) and intellectual disability (ID) are neurodevelopmental
disorders with large genetic components, but identification of pathogenic genes has …

Genetic epidemiology is the study of inherited factors involved in the etiology of a disease or
disorder and uses the methods of both medical genetics and clinical epidemiology. In …

Autism is an etiologically and clinically heterogeneous group of disorders, diagnosed solely
by the complex behavioral phenotype. On the basis of the high-heritability index, geneticists …

Despite compelling evidence from twin and family studies indicating a strong genetic
involvement in the etiology of autism, the unequivocal detection of autism susceptibility …

Although no definitive genetic mutations leading to autism susceptibility have been
established, the field has many new resources to tackle this difficult problem. Numbers of …

Over the past years, autism researchers have become increasingly aware of the limitations
of candidate gene analysis with previous, somewhat naive, approaches based on unknown …