Objective Cholesterol gallstone disease (CGD) is a multifactorial and multistep disease.
Apart from female gender and increasing age being the documented non-modifiable risk …

Abstract Background and Aim: Gallstone formation is characterized by the abnormal
regulation of cholesterol trafficking and solubilization. The prevalence of gallstone disease …

Background Gallstones are abnormal masses caused by impaired metabolism of
cholesterol, bilirubin, or bile salts in the gallbladder or biliary tract. ATP-binding cassette …

Aim: Gallstone disease is an important cause of abdominal morbidity Organic anion
transport protein 1B1 (OATP1B1)(encoded by SLCO1B1) is a major transporter protein for …

Abstract Background and Aim: The excretion of cholesterol from the liver is regulated by the
ATP‐binding cassette transporter ABCG8. A common genetic polymorphism D19H of …

Gallstone disease (GSD) is the result of the interaction between genetic and environmental
factors and it is a major disease cause of surgery with high costs to health systems …

Background The overexpression of the cholesterol transporter: ATP-binding cassette
transporter (ABCG8) due to the effect of ABCG8 genetic variant (rs11887534) leads to the …

Background & Aims A genome-wide association study (GWAS) of 280 cases identified the
hepatic cholesterol transporter ABCG8 as a locus associated with risk for gallstone disease …

Background In this study, we evaluated the association between these polymorphisms and
gallstone disease using meta-analysis and compared the hepatic ABCG5/G8 mRNA …

Cholesterol gallstone disease is one of the most common digestive diseases, with an overall
prevalence of 10–20%. Although a common and economically-relevant problem in …