Effects of SLC10A2 variant rs9514089 on gallstone risk and serum cholesterol levels- meta-analysis of three independent cohorts

A Tönjes, H Wittenburg, J Halbritter, O Renner… - BMC medical …, 2011 - Springer
Background Recently, a single nucleotide polymorphism (SNP) rs9514089 in SLC10A2
(apical sodium-dependent bile acid transporter gene) has been identified as a susceptibility …

[HTML][HTML] Genetic variants involved in gallstone formation and capsaicin metabolism, and the risk of gallbladder cancer in Chilean women

S Báez, Y Tsuchiya, A Calvo, M Pruyas… - World journal of …, 2010 - ncbi.nlm.nih.gov
AIM: To determine the effects of genetic variants associated with gallstone formation and
capsaicin (a pungent component of chili pepper) metabolism on the risk of gallbladder …

Polymorphisms in ABCG5/G8 transporters linked to hypercholesterolemia and gallstone disease

I Rudkowska, PJH Jones - Nutrition reviews, 2008 - academic.oup.com
ATP-binding cassette (ABC) transporters function in the homeostasis of lipids. Dysfunction of
ABC transporters is frequently associated with disease. This review examines links between …

Risk profile for gallstone disease in southern Indian population: is there anything new?

AP Chandran, R Sivarajan, V Srinivasan… - Indian Journal of …, 2014 - Springer
Aim There are reports of changes in demographic and morphological characteristics of
gallstone (GS) disease in South Asian countries. The changes in dietary factors have not …

Autosomal genome-wide linkage analysis to identify loci for gallbladder wall thickness in Mexican Americans

N Samudrala, VS Farook, GD Dodd, S Puppala… - Human biology, 2008 - BioOne
The significance of gallbladder wall thickness (GBWT) in regard to gallbladder disease
(GBD) is not completely understood. Thickening of the gallbladder wall has been observed …

Obesity, adiposity, and risk of symptomatic gallstone disease according to genetic susceptibility

J Lim, J Wirth, K Wu, E Giovannucci, P Kraft… - Clinical …, 2022 - Elsevier
Background & Aims Adiposity has been consistently associated with gallstone disease risk.
We aimed to characterize associations of anthropometric measures (body mass index [BMI] …

Pathogenesis of gallstones: a genetic perspective

F Grünhage, F Lammert - Best Practice & Research Clinical …, 2006 - Elsevier
Cholelithiasis is one of the most prevalent gastroenterological diseases, imposing a huge
economic burden on health-care systems. Gallbladder stones form when the concentration …

Cholesterol metabolism gene polymorphisms and the risk of biliary tract cancers and stones: a population-based case-control study in Shanghai, China

HL Xu, JR Cheng, G Andreotti, YT Gao… - …, 2011 - academic.oup.com
Biliary tract cancers are rare but fatal malignancies, with increasing incidence in Shanghai,
China. Gallstones, the primary risk factor for biliary tract cancer, typically result from …

[HTML][HTML] Recent advances in understanding and managing cholesterol gallstones

A Di Ciaula, P Portincasa - F1000Research, 2018 - ncbi.nlm.nih.gov
The high prevalence of cholesterol gallstones, the availability of new information about
pathogenesis, and the relevant health costs due to the management of cholelithiasis in both …

Cholesterol gallstones and cancer of gallbladder (CAGB): molecular links

A Venniyoor - Medical hypotheses, 2008 - Elsevier
There is a known association between cholesterol gallstones and cancer of gall bladder
(CAGB). However, the exact relation is not clear. It is proposed they are linked at molecular …