ATP-binding cassette (ABC) transporters function in the homeostasis of lipids. Dysfunction of
ABC transporters is frequently associated with disease. This review examines links between …

The significance of gallbladder wall thickness (GBWT) in regard to gallbladder disease
(GBD) is not completely understood. Thickening of the gallbladder wall has been observed …

Background & Aims Adiposity has been consistently associated with gallstone disease risk.
We aimed to characterize associations of anthropometric measures (body mass index [BMI] …

Cholelithiasis is one of the most prevalent gastroenterological diseases, imposing a huge
economic burden on health-care systems. Gallbladder stones form when the concentration …

Biliary tract cancers are rare but fatal malignancies, with increasing incidence in Shanghai,
China. Gallstones, the primary risk factor for biliary tract cancer, typically result from …

The high prevalence of cholesterol gallstones, the availability of new information about
pathogenesis, and the relevant health costs due to the management of cholelithiasis in both …

There is a known association between cholesterol gallstones and cancer of gall bladder
(CAGB). However, the exact relation is not clear. It is proposed they are linked at molecular …

Background & Aims Obesity, type 2 diabetes, and lifestyle factors (cigarette smoking, alcohol
drinking, and coffee consumption) have been associated with the risk of developing …

Investigations into the molecular mechanisms of cholestasis have revealed intricate and
intriguing details of bile salt metabolism as well as its regulatory mechanisms in health and …

Gallstone disease (GSD) is a major global health problem that causes high morbidity and
mortality constituting a significant economic burden in developed countries (Shaffer, 2006; …