[HTML][HTML] Does depression in mid-life predispose to greater cognitive decline in later life in the Whitehall II cohort?

LI Sinclair, HA Ball, BM Bolea-Alamanac - Journal of Affective Disorders, 2023 - Elsevier
Background Later-life depression appears to have different symptomatology and possibly
underlying pathology to younger adults. Depression is linked to dementia but whether it is a …

Recurrent depression has persistent effects on cognition but this does not appear to be mediated by neuroinflammation

LI Sinclair, HA Ball, S Bauermeister… - Journal of Affective …, 2022 - Elsevier
Background Later-life depression appears to be different to depression in younger adults.
The underlying pathology may also differ. Depression is linked to dementia but whether it is …

Persistent depressive symptoms and cognitive function in late midlife: the Whitehall II study

A Singh-Manoux, TN Akbaraly… - The Journal of …, 2010 - legacy.psychiatrist.com
Objective: Depression has been widely linked to poor cognition and dementia in the elderly.
However, comorbidity at older ages does not allow an assessment of the role of mental …

Depressive symptoms and cognitive decline in older adults

M Forbes, M Lotfaliany, M Mohebbi… - International …, 2024 - cambridge.org
Objectives: Few studies have examined the impact of late-life depression trajectories on
specific domains of cognitive function. This study aims to delineate how different depressive …

Persistent depressive symptoms and cognitive decline in older adults

F Zheng, B Zhong, X Song, W Xie - The British Journal of Psychiatry, 2018 - cambridge.org
BackgroundLittle is known about the effect of persistent depressive symptoms on the
trajectory of cognitive decline. AimsWe aimed to investigate the longitudinal association …

Depressive symptoms and cognitive decline: a longitudinal analysis of potentially modifiable risk factors in community dwelling older adults

D Gallagher, A Kiss, K Lanctot, N Herrmann - Journal of affective disorders, 2016 - Elsevier
Background Depressive symptoms have been associated with increased risk of cognitive
decline in later life. There are no interventions proven to reduce risk of cognitive decline in …

The association between late-life depression, mild cognitive impairment and dementia: is inflammation the missing link?

AP Hermida, WM McDonald, K Steenland… - Expert review of …, 2012 - Taylor & Francis
Depression, mild cognitive impairment (MCI) and dementia are highly prevalent conditions
that are increasing exponentially with similarly expanding social, medical and economic …

Depression, dementia and immune dysregulation

S Hayley, AM Hakim, PR Albert - Brain, 2021 - academic.oup.com
Major depression is a prevalent illness that increases the risk of several neurological
conditions. These include stroke, cardiovascular disease, and dementia including …

Depressive symptoms and cognitive decline in elderly people: longitudinal study

S Paterniti, MH Verdier-Taillefer, C Dufouil… - The British Journal of …, 2002 - cambridge.org
BackgroundDepressive symptoms are associated with cognitive decline in elderly people,
but the nature of their temporal relationship remains equivocal. AimsTo test whether …

Longitudinal associations between late-life depression dimensions and cognitive functioning: a cross-domain latent growth curve analysis

A Brailean, MJ Aartsen, G Muniz-Terrera… - Psychological …, 2017 - cambridge.org
BackgroundCognitive impairment and depression often co-occur in older adults, but it is not
clear whether depression is a risk factor for cognitive decline, a psychological reaction to …