[HTML][HTML] Pathophysiology of obesity on knee joint homeostasis: contributions of the infrapatellar fat pad

KS Santangelo, LB Radakovich, J Fouts… - … molecular biology and …, 2016 - degruyter.com
Osteoarthritis (OA) is a debilitating condition characterized by inflammation, breakdown, and
consequent loss of cartilage of the joints. Epidemiological studies indicate obesity is an …

Adipokines: new therapeutic target for osteoarthritis?

C Xie, Q Chen - Current rheumatology reports, 2019 - Springer
Abstract Purpose of the Review Osteoarthritis (OA) is an aging-associated and injury-
induced joint disease characterized by cartilage degradation, bone sclerosis, and persistent …

The levels of the adipokines adipsin and leptin are associated with knee osteoarthritis progression as assessed by MRI and incidence of total knee replacement in …

J Martel-Pelletier, JP Raynauld, M Dorais… - …, 2016 - academic.oup.com
Objective. Limited studies have explored the association between adipokines and knee OA
structural progression using quantitative MRI (qMRI), and very few have included total knee …

Pro-inflammatory cytokines: The link between obesity and osteoarthritis

T Wang, C He - Cytokine & growth factor reviews, 2018 - Elsevier
Osteoarthritis (OA), characterized by joint malfunction and chronic disability, is the most
common form of arthritis. Clinical and animal experiments reveal that age-related OA is …

[PDF][PDF] The infrapatellar fat pad induces inflammatory and degradative effects in articular cells but not through leptin or adiponectin

JB Gross, C Guillaume, P Gegout-Pottie… - Clin Exp …, 2017 - clinexprheumatol.org
The infrapatellar fat pad induces inflammatory and degradative effects in articular cells but not
through leptin or adiponectin Page 1 Clinical and Experimental Rheumatology 2017; 35: 53-60 …

Source and hub of inflammation: The infrapatellar fat pad and its interactions with articular tissues during knee osteoarthritis

S Zhou, T Maleitzke, S Geissler… - Journal of …, 2022 - Wiley Online Library
Knee osteoarthritis, the most prevalent degenerative joint disorder worldwide, is driven by
chronic low‐grade inflammation and subsequent cartilage degradation. Clinical data on the …

[HTML][HTML] Pathogenic mechanisms and therapeutic approaches in obesity-related knee osteoarthritis

R Shumnalieva, G Kotov, P Ermencheva, S Monov - Biomedicines, 2023 - mdpi.com
The knee is the joint most frequently involved in osteoarthritis, a common joint disorder in the
adult population that is associated with significant chronic joint pain, reduced mobility and …

[HTML][HTML] Systemic and local adipose tissue in knee osteoarthritis

J Chang, Z Liao, M Lu, T Meng, W Han… - Osteoarthritis and cartilage, 2018 - Elsevier
Knee osteoarthritis (OA) is the most common joint disease. Body adipose tissue has been
shown to be related to the development and progression of knee OA. Among systemic …

[HTML][HTML] Adipokines: Biomarkers for osteoarthritis?

T Poonpet, S Honsawek - World journal of orthopedics, 2014 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is one of the most common degenerative joint diseases in aging
population. Obesity is an important risk factor for initiation and progression of OA. It is …

[HTML][HTML] The role of adipocytokines in the pathogenesis of knee joint osteoarthritis

M Richter, T Trzeciak, M Owecki, A Pucher… - International …, 2015 - Springer
Osteoarthritis (OA) is one of the most common causes of musculoskeletal disability in the
world. Traditionally, it has been thought that obesity contributes to the development and …