Abstract According to the International Agency for Research of Cancer, an institution of the
World Health Organization, in 2020 an estimate of 19.3 million humans were diagnosed with …

Molecular photoswitches transform light energy into reversible structural changes. Their
combination with known pharmacophores often allows for photomodulation of the biological …

Photocontrolled, biologically active compounds are an emerging class of" smart" drug
candidates. They provide additional safety in systemic chemotherapy due to their precise …

Aim: To verify whether photocontrol of biological activity could augment safety of a
chemotherapeutic agent. Materials & methods: LD50 values for gramicidin S and …

Hemipiperazines are a recently discovered class of peptide‐derived molecular
photoswitches with high biocompatibility and therapeutic potential. Here, for the first time we …

Azobenzene analogues of the tubulin polymerisation inhibitor combretastatin A4 (PSTs)
were previously developed to optically control microtubule dynamics in living systems, with …

Photocontrol of biological processes with light‐sensitive molecules offers great advantages
for basic research and applied purposes. Cancer, infections, and diseases of the cardiac …

Photopharmacology is a growing area of endeavor that employs photoswitchable ligands to
allow for light-dependent pharmacological activity. By coupling light to therapeutic action …

Tubulin Polymerization Inhibitors (TPIs) are promising ligands utilized in chemotherapy for
modern cancer treatment. However, the current TPIs exhibit many serious side effects that …

Diarylethene derivatives, the biological activity of which can be reversibly changed by
irradiation with light of different wavelengths, have shown promise as scientific tools and as …