Altered gene expression patterns in MCF-7 cells induced by the urban dust particulate complex mixture standard reference material 1649a

B Mahadevan, C Keshava, T Musafia-Jeknic, A Pecaj… - Cancer research, 2005 - AACR
Human exposures to polycyclic aromatic hydrocarbon (PAH) occur in complex mixtures.
Here, gene expression patterns were investigated using standard reference material (SRM) …

Long-term effects of a standardized complex mixture of urban dust particulate on the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons in human …

T Musafia-Jeknic, B Mahadevan, C Pereira… - Toxicological …, 2005 - academic.oup.com
Humans are exposed to complex mixtures of polycyclic aromatic hydrocarbons in the
atmosphere. We examined the long term effects of a standard reference material (SRM) …

Urban dust particulate matter alters PAH-induced carcinogenesis by inhibition of CYP1A1 and CYP1B1

LA Courter, T Musafia-Jeknic, K Fischer… - Toxicological …, 2007 - academic.oup.com
The polycyclic aromatic hydrocarbons (PAHs) benzo [a] pyrene (B [a] P) and dibenzo [a, l]
pyrene (DB [a, l] P) are well-studied environmental carcinogens, however, their potency …

Effect of artificial mixtures of environmental polycyclic aromatic hydrocarbons present in coal tar, urban dust, and diesel exhaust particulates on MCF‐7 cells in culture

B Mahadevan, H Parsons, T Musafia… - Environmental and …, 2004 - Wiley Online Library
Human exposure to polycyclic aromatic hydrocarbons (PAHs) occurs through complex
mixtures. The National Institute of Standards and Technology has established standard …

Activation of the aryl hydrocarbon receptor is the major toxic mode of action of an organic extract of a reference urban dust particulate matter mixture: the role of …

Z Andrysík, J Vondráček, S Marvanová… - Mutation Research …, 2011 - Elsevier
Many of the toxic and carcinogenic effects of urban air pollution have been linked to
polycyclic aromatic hydrocarbons (PAHs) adsorbed to airborne particulate matter (PM). The …

Effect of a complex environmental mixture from coal tar containing polycyclic aromatic hydrocarbons (PAH) on the tumor initiation, PAH–DNA binding and metabolic …

CP Marston, C Pereira, J Ferguson, K Fischer… - …, 2001 - academic.oup.com
Human exposure to polycyclic aromatic hydrocarbons (PAH) occurs through complex
mixtures such as coal tar. The effect of complex PAH mixtures on the activation of …

Genotoxic potential of polycyclic aromatic hydrocarbons-coated onto airborne particulate matter (PM2. 5) in human lung epithelial A549 cells

S Billet, I Abbas, J Le Goff, A Verdin, V André… - Cancer Letters, 2008 - Elsevier
To improve the knowledge of the underlying mechanisms of action involved in air pollution
Particulate Matter (PM)-induced toxicity in human lungs, with a particular interest of the …

Polycyclic aromatic hydrocarbons (PAHs) in different indoor dusts and their potential cytotoxicity based on two human cell lines

Y Kang, KC Cheung, MH Wong - Environment International, 2010 - Elsevier
In this study, 55 air-conditioner filter dust samples from six different workplaces including
commercial office, secondary school, shopping mall, hospital, electronic factory and …

Time- and dose-dependent DNA binding of PAHs derived from diesel particle extracts, benzo[a]pyrene and 5-methylchrysene in a human mammary carcinoma cell …

T Kuljukka-Rabb, K Peltonen, S Isotalo… - …, 2001 - academic.oup.com
Cultures of a human mammary carcinoma cell line (MCF-7) were exposed to the soluble
organic fraction of diesel particle emissions, benzo [a] pyrene (B [a] P) and 5 …

Polycyclic aromatic hydrocarbons (PAHs) in indoor environments are still imposing carcinogenic risk

M Wang, S Jia, SH Lee, A Chow, M Fang - Journal of Hazardous Materials, 2021 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are among the most health-relevant air pollutants.
Herein, we conducted meta-analysis and experimental validation to evaluate PAHs in our …