Lung cancer associated with combustion particles and fine particulate matter (PM2. 5)-The roles of polycyclic aromatic hydrocarbons (PAHs) and the aryl hydrocarbon …

JA Holme, J Vondráček, M Machala… - Biochemical …, 2023 - Elsevier
Air pollution is the leading cause of lung cancer after tobacco smoking, contributing to 20%
of all lung cancer deaths. Increased risk associated with living near trafficked roads …

Dose-related differences in DNA adduct levels rodent tissues followhlg skin application of complex mixtures from air pollution sources

JE Gallagher, MA Jackson, MH George… - …, 1990 - academic.oup.com
Dose-related differences in the binding of DNA reactive intermediates for three
environmentally important complex mixture particulate extracts and a well-studied …

[HTML][HTML] Sources, distribution and toxicity of polyaromatic hydrocarbons (PAHs) in particulate matter

BK Lee - Air pollution, 2010 - intechopen.com
Polycyclic aromatic hydrocarbons (PAHs) are a group of organic compounds consisting of
two or more fused aromatic rings. PAHs originate mainly from anthropogenic processes …

Environmentally prevalent polycyclic aromatic hydrocarbons can elicit co-carcinogenic properties in an in vitro murine lung epithelial cell model

AK Bauer, K Velmurugan, S Plöttner, KJ Siegrist… - Archives of …, 2018 - Springer
Low molecular weight (LMW) polycyclic aromatic hydrocarbons (PAH) are the most
abundant PAHs environmentally, occupationally, and are in cigarette smoke; however, little …

Xenobiotic metabolism induction and bulky DNA adducts generated by particulate matter pollution in BEAS‐2B cell line: geographical and seasonal influence

C Lepers, V André, M Dergham, S Billet… - Journal of Applied …, 2014 - Wiley Online Library
Airborne particulate matter (PM) toxicity is of growing interest as diesel exhaust particles
have been classified as carcinogenic to humans. However, PM is a mixture of chemicals …

Transcriptional Signature of Human Macrophages Exposed to the Environmental Contaminant Benzo(a)pyrene

L Sparfel, ML Pinel-Marie, M Boize… - Toxicological …, 2010 - academic.oup.com
Polycyclic aromatic hydrocarbons (PAHs) are widely distributed immunotoxic and
carcinogenic environmental contaminants, known to affect macrophages. In order to identify …

Aryl hydrocarbon receptor-mediated activity of atmospheric particulate matter from an urban and a rural site in Switzerland

D Wenger, AC Gerecke, NV Heeb, C Hueglin… - Atmospheric …, 2009 - Elsevier
Atmospheric particulate matter (PM) is an air-suspended mixture of solid and liquid particles
that vary in size, shape, and chemical composition. Long-term exposure to elevated …

Effect of polyaryl hydrocarbons on cytotoxicity in monocytic cells: Potential role of cytochromes P450 and oxidative stress pathways

S Ranjit, NM Midde, N Sinha, BJ Patters, MA Rahman… - PloS one, 2016 - journals.plos.org
Background Benzo (a) pyrene (BaP), naphthalene (NPh), phenanthrene (Phe), benzo (a)
antharacene (BeA), and benzo (b) fluoranthene (BeF) are known carcinogenic polyaryl …

Binary PAH mixtures cause additive or antagonistic effects on gene expression but synergistic effects on DNA adduct formation

YCM Staal, DGAJ Hebels, MH Van Herwijnen… - …, 2007 - academic.oup.com
Polycyclic aromatic hydrocarbons (PAHs) cover a wide range of structurally related
compounds which differ greatly in their carcinogenic potency. PAH exposure usually occurs …

Bioavailability and potential carcinogenicity of polycyclic aromatic hydrocarbons from wood combustion particulate matter in vitro

S Gauggel-Lewandowski, AH Heussner… - Chemico-biological …, 2013 - Elsevier
Due to increasing energy demand and limited fossil fuels, renewable energy sources have
gained in importance. Particulate matter (PM) in general, but also PM from the combustion of …