Rivaroxaban in the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation: clinical implications of the ROCKET AF trial and its …

RJ Spencer, JV Amerena - American Journal of Cardiovascular Drugs, 2015 - Springer
Atrial fibrillation (AF) is an increasingly common cause of stroke and systemic embolism.
While warfarin has been the mainstay of stroke prevention in patients with AF, newer novel …

Rivaroxaban: a review of its use in the prevention of stroke and systemic embolism in patients with atrial fibrillation

NJ Carter, GL Plosker - Drugs, 2013 - Springer
Rivaroxaban (Xarelto®), a direct factor Xa inhibitor, is approved for the prevention of stroke
and systemic embolism in patients with atrial fibrillation (AF) in Canada or those with …

Rivaroxaban as an oral anticoagulant for stroke prevention in atrial fibrillation

AGG Turpie - Therapeutics and clinical risk management, 2014 - Taylor & Francis
Atrial fibrillation (AF) is the most common cardiac arrhythmia in the developed world and is
associated with a fivefold increase in the risk of stroke, accounting for up to 15% of strokes in …

Rivaroxaban—once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation: rationale …

Executive Steering Committee… - American heart …, 2010 - Elsevier
BACKGROUND: Atrial fibrillation (AF), the most common significant cardiac arrhythmia,
increases the risk of stroke, particularly in the elderly. Warfarin is effective in reducing stroke …

Role of rivaroxaban in the management of atrial fibrillation: insights from clinical practice

K Vimalesvaran, SJ Dockrill… - Vascular Health and Risk …, 2018 - Taylor & Francis
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and it leads to
significant morbidity and mortality, predominantly from ischemic stroke. Vitamin K …

Rivaroxaban and stroke prevention in patients with atrial fibrillation: new evidence

A Martínez-Rubio, GA Dan, JC Kaski - Expert Review of …, 2014 - Taylor & Francis
In the majority of patients with non-valvular atrial fibrillation (AF) anticoagulation is required
to reduce the risk of stroke. Although vitamin K antagonists effectively reduce the risk of …

Rivaroxaban for stroke prevention in atrial fibrillation: a critical review of the ROCKET AF trial

JS Paikin, JJ Manolakos… - Expert review of …, 2012 - Taylor & Francis
Oral anticoagulation is the mainstay of therapy for stroke prevention in patients with atrial
fibrillation (AF). Vitamin K antagonists such as warfarin have many drawbacks that reduce …

Rivaroxaban in patients with atrial fibrillation: from ROCKET AF to everyday practice

G Barón-Esquivias, F Marín… - Expert Review of …, 2017 - Taylor & Francis
Introduction: Registries and non-interventional studies offer relevant and complementary
information to clinical trials, since they have a high external validity. Areas covered: The …

Stroke prevention with rivaroxaban in higher‐risk populations with atrial fibrillation

HC Diener, JL Halperin, K Fox… - International Journal of …, 2015 - Wiley Online Library
Background Atrial fibrillation (AF), the most common cardiac arrhythmia, is a major risk factor
for stroke. Rivaroxaban, an oral factor Xa inhibitor, is approved for the prevention of stroke in …

Practical guidance for using rivaroxaban in patients with atrial fibrillation: balancing benefit and risk

S Haas, C Bode, B Norrving… - Vascular health and risk …, 2014 - Taylor & Francis
Rivaroxaban is a direct factor Xa inhibitor that is widely available to reduce the risk of stroke
or systemic embolism in patients with nonvalvular atrial fibrillation and one or more risk …