New insights into the pathogenesis and genetics of psoriatic arthritis

KE Nograles, RD Brasington… - Nature clinical practice …, 2009 - nature.com
Psoriasis vulgaris and psoriatic arthritis (PsA) are inter-related heritable diseases. Psoriatic
skin is characterized by hyperproliferative, poorly differentiated keratinocytes and severe …

Genetics of psoriatic arthritis

DD O'Rielly, P Rahman - Best practice & research Clinical rheumatology, 2014 - Elsevier
Spondyloarthritis (SpA) represents a group of inflammatory rheumatic diseases that cluster
within families and possess overlapping clinical features. The pathogenesis of SpA …

Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis

J Bowes, A Budu-Aggrey, U Huffmeier, S Uebe… - Nature …, 2015 - nature.com
Psoriatic arthritis (PsA) is a chronic inflammatory arthritis associated with psoriasis and,
despite the larger estimated heritability for PsA, the majority of genetic susceptibility loci …

Psoriatic arthritis

O FitzGerald, A Ogdie, V Chandran… - Nature reviews Disease …, 2021 - nature.com
Psoriatic arthritis (PsA) is a complex inflammatory disease with heterogeneous clinical
features, which complicates psoriasis in 30% of patients. There are no diagnostic criteria or …

Genetics of susceptibility and treatment response in psoriatic arthritis

DD O'Rielly, P Rahman - Nature Reviews Rheumatology, 2011 - nature.com
Psoriatic arthritis (PsA), an inflammatory arthritis associated with psoriasis, has a wide
spectrum of disease severity. The clinical heterogeneity in PsA probably reflects substantial …

The genetics of psoriasis and psoriatic arthritis

DD O'Rielly, M Jani, P Rahman, JT Elder - The Journal of Rheumatology …, 2019 - jrheum.org
Psoriatic arthritis (PsA) is an inflammatory arthritis that manifests in 20–30% of patients
diagnosed with psoriasis. Epidemiologic studies suggest a substantial genetic contribution …

Genetic epidemiology of psoriasis and psoriatic arthritis

P Rahman, JT Elder - Annals of the rheumatic diseases, 2005 - ard.bmj.com
Psoriasis and psoriatic arthritis (PsA) are interrelated disorders, as most patients with PsA
also have psoriasis. Thus it is not surprising that epidemiological and immunogenetic …

Genetics of psoriasis and psoriatic arthritis: update and future direction

KC Duffin, V Chandran, DD Gladman… - The Journal of …, 2008 - jrheum.org
Psoriasis and psoriatic arthritis (PsA) both have substantive genetic determinants.
Numerous candidate regions and genes have now been replicated in disease susceptibility …

Psoriatic arthritis: an update

P Lloyd, C Ryan, A Menter - Arthritis, 2012 - Wiley Online Library
Psoriatic arthritis is a debilitating condition, which affects approximately one‐quarter of
psoriasis patients. Recent findings have furthered our understanding of the complex …

[HTML][HTML] The genetics of psoriatic arthritis: lessons from genome-wide association studies

J Bowes, A Barton - Discovery medicine, 2010 - discoverymedicine.com
Psoriatic arthritis (PsA) occurs in approximately 30% of psoriasis patients. Understanding
the similarities and differences in the etiology of these related diseases may highlight …