Creating the amylin story

TA Lutz - Appetite, 2022 - Elsevier
This paper is based on a presentation given at the Annual Meeting of the Society for the
Study of Ingestive Behavior in July 2021 and provides a personal view on some of the …

The acute effect of amylin and salmon calcitonin on energy expenditure

PY Wielinga, B Alder, TA Lutz - Physiology & behavior, 2007 - Elsevier
The pancreatic B-cell hormone amylin is known to be involved in the regulation of meal
ending satiation and it also shares typical features of adiposity signals. Chronic amylin …

Pharmacological characterization of rat amylin receptors: implications for the identification of amylin receptor subtypes

RJ Bailey, CS Walker, AH Ferner… - British journal of …, 2012 - Wiley Online Library
BACKGROUND AND PURPOSE Amylin (Amy) is an important glucoregulatory peptide and
AMY receptors are clinical targets for diabetes and obesity. Human (h) AMY receptor …

Amygdala, an important regulator for food intake

Q Zhang, H Li, F Guo - Frontiers in Biology, 2011 - Springer
Amygdala plays a critical role in the regulation of emotional behavior and food intake.
Neuropeptides are short chains of amino acids secreted by neurons as intercellular …

Effects of amylin on appetite regulation and memory

JF Flood, SA Farr, HJ Perry Iii, FE Kaiser… - Canadian journal of …, 1995 - cdnsciencepub.com
Amylin has been demonstrated to decrease food intake in mice and rats. Amylin is effective
when delivered both peripherally and directly into the central nervous system. Amylin's effect …

Amylin selectively signals onto POMC neurons in the arcuate nucleus of the hypothalamus

TA Lutz, B Coester, L Whiting, AA Dunn-Meynell… - Diabetes, 2018 - Am Diabetes Assoc
Amylin phosphorylates ERK (p-ERK) in the area postrema to reduce eating and synergizes
with leptin to phosphorylate STAT3 in the arcuate (ARC) and ventromedial (VMN) …

The central anorexigenic mechanism of amylin in Japanese quail (Coturnix japonica) involves pro-opiomelanocortin, calcitonin receptor, and the arcuate nucleus of …

YJW Yuan JingWei, ER Gilbert, MA Cline - 2017 - cabidigitallibrary.org
Amylin is a 37-amino acid peptide hormone that exerts anorexigenic effects in humans and
animals. We demonstrated that central injection of amylin into chicks affected feeding and …

Pharmacological actions of the peptide hormone amylin in the long-term regulation of food intake, food preference, and body weight

C Mack, J Wilson, J Athanacio… - American Journal …, 2007 - journals.physiology.org
The ability of amylin to reduce acute food intake in rodents is well established. Longer-term
administration in rats (up to 24 days) shows a concomitant reduction in body weight …

Whole Brain cFos Response to Different Amylin Receptor Agonists

U Roostalu, G Skovbjerg, J Perens, CG Salinas… - …, 2022 - search.proquest.com
Background: The pancreatic hormone amylin plays a central role in energy homeostasis by
stimulating satiation and reducing food reward, making amylin receptor agonists attractive …

The anorectic effect of a chronic peripheral infusion of amylin is abolished in area postrema/nucleus of the solitary tract (AP/NTS) lesioned rats

TA Lutz, A Mollet, PA Rushing, T Riediger… - International journal of …, 2001 - nature.com
OBJECTIVE: Neurons in the area postrema/nucleus of the solitary tract (AP/NTS) region
mediate amylin's anorectic effect elicited by a single intraperitoneal (ip) injection of a low …