Ligand-mediated Targeted Drug Delivery Approaches against Hepatocellular Carcinoma

A Singh, S Mishra, S Sharma, S Ojha… - Current Cancer Drug …, 2023 - ingentaconnect.com
One of the most important health problems in the world today is cancer. The World Health
Organization (WHO) reported that it results in 8.9 million deaths annually. Malignant tumours …

[PDF][PDF] Drug targeting strategies for liver cancer and other liver diseases

S Shilpi, R Shivvedi, E Gurnany, S Dixit… - MOJ Drug Des. Dev …, 2018 - academia.edu
Abstract Treatment of liver cancer and other diseases are a challenging task for the current
researchers in the pharmaceutical field. There are some physiological barriers like RES …

Ligand-based targeted therapy: a novel strategy for hepatocellular carcinoma

M Li, W Zhang, B Wang, Y Gao, Z Song… - International Journal of …, 2016 - Taylor & Francis
Hepatocellular carcinoma (HCC) is the most common primary liver cancer with high
morbidity and mortality worldwide. Chemotherapy is recommended to patients with …

Drug delivery system targeting advanced hepatocellular carcinoma: Current and future

X Zhang, HLH Ng, A Lu, C Lin, L Zhou, G Lin… - … , Biology and Medicine, 2016 - Elsevier
Hepatocellular carcinoma (HCC) has a fairly high morbidity and is notoriously difficult to treat
due to long latent period before detection, multidrug resistance and severe drug-related …

[HTML][HTML] Precision targeting in hepatocellular carcinoma: Exploring ligand-receptor mediated nanotherapy

XQ Zhou, YP Li, SS Dang - World Journal of Hepatology, 2024 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and poses a
major challenge to global health due to its high morbidity and mortality. Conventional …

A Comprehensive Review on Liver Targeting: Emphasis on Nanotechnology-based Molecular Targets and Receptors Mediated Approaches

AK Mishra, M Pandey, HK Dewangan, N Sl… - Current Drug …, 2022 - ingentaconnect.com
Background: The pathogenesis of hepatic diseases involves several cells, which
complicates the delivery of pharmaceutical agents. Many severe liver diseases affecting the …

Concepts and Strategies for the Site Specific Delivery of Nanocarrier Based Delivery Systems for Treating Hepatocellular Carcinoma.

P Sharma, A Pandita, RS Murthy - Current Drug Delivery, 2013 - europepmc.org
Hepatocellular carcinoma (HCC) is most common lethal malignancy worldwide. About 80%
of liver cancer cases are attributed to the combined effects of Hepatitis B and C virus …

Role of nanomedicine in hepatic targeting-deciphering strategies with molecular insights and preclinical prospects

V Dhawan, M Marwah, M Nagarsenker - Drug Delivery Letters, 2018 - ingentaconnect.com
Background: Nanoformulation strategies that render spatial placement and temporal
delivery of drugs feasible, can be of utility in delivering the drug specifically to afflicted liver …

Nanocarrier-based tumor-targeting drug delivery systems for hepatocellular carcinoma treatments: Enhanced therapeutic efficacy and reduced drug toxicity

T Tian, J Ruan, J Zhang, CX Zhao… - Journal of biomedical …, 2022 - ingentaconnect.com
Hepatocellular carcinoma (HCC), due to the lack of efficient diagnostic methods and short of
available treatments, becomes the third main cause of cancer deaths. Novel treatments for …

New molecular targets for functionalized nanosized drug delivery systems in personalized therapy for hepatocellular carcinoma

C Turato, A Balasso, V Carloni, C Tiribelli… - Journal of Controlled …, 2017 - Elsevier
Hepatocellular carcinoma, the most frequent solid tumor of the liver, has a very poor
prognosis, being the second most common cause of death from cancer worldwide. The …