Advances in receptor‐mediated, tumor‐targeted drug delivery

DE Large, JR Soucy, J Hebert… - Advanced …, 2019 - Wiley Online Library
Receptor‐mediated drug delivery presents an opportunity to enhance therapeutic efficiency
by accumulating drug within the tissue of interest and reducing undesired, off‐target effects …

Asialoglycoprotein receptor targeted delivery of doxorubicin nanoparticles for hepatocellular carcinoma

S Pranatharthiharan, MD Patel, VC Malshe, V Pujari… - Drug …, 2017 - Taylor & Francis
We report asialoglycoprotein receptor (ASGPR)-targeted doxorubicin hydrochloride (Dox)
nanoparticles (NPs) for hepatocellular carcinoma (HCC). Polyethylene sebacate (PES) …

Nanomedicine in management of hepatocellular carcinoma: challenges and opportunities

NK Mohamed, MA Hamad, MZE Hafez… - … Journal of Cancer, 2017 - Wiley Online Library
Hepatocellular carcinoma is the second leading cause of cancer deaths worldwide. It is
characterized by unique features that can be utilized for selective and targeted therapy …

Shell cross-linked and hepatocyte-targeting nanoparticles containing doxorubicin via acid-cleavable linkage

C Lu, MMQ Xing, W Zhong - Nanomedicine: Nanotechnology, Biology and …, 2011 - Elsevier
Hepatocyte-targeting and shell cross-linked nanoparticles with lactose moiety on the surface
and doxorubicin (DOX) in the core were prepared from lactose-PEG-DOX conjugate. The …

Receptor mediated tumor targeting: an emerging approach for cancer therapy

C Mohanty, M Das, JR Kanwar… - Current drug …, 2011 - ingentaconnect.com
Receptor-mediated tumor targeting has received major attention in the field of cancer drug
delivery in the past few years. Receptors, as molecular target has opened new opportunities …

Recent advances in drug delivery nanocarriers for targeting hepatocellular carcinoma

S Wang, Q Lv, X Li - Journal of Nanomaterials, 2022 - Wiley Online Library
Hepatocellular carcinoma (HCC) is among the primary drivers of cancer‐related death
globally, owing to the ineffectiveness of treatments in intermediate and terminal stages—an …

[HTML][HTML] Targeted delivery of cytotoxic drugs: Challenges, opportunities and new developments

S Cazzamalli, A Dal Corso, D Neri - Chimia, 2017 - ncbi.nlm.nih.gov
Cytotoxic drugs, which are commonly used for the pharmacotherapy of many forms of
cancer, often cause substantial toxicity to the patient without being able to induce long …

Bifunctional compounds for targeted hepatic gene delivery

KS Kim, Y Lei, DB Stolz, D Liu - Gene therapy, 2007 - nature.com
A series of bifunctional compounds with galactosyl residues as targeting ligand for
asialoglycoprotein receptors on hepatocytes and various dendrimers as the DNA-binding …

[引用][C] Targeted drug delivery: a review

N Mishra, P Pant, A Porwal, J Jaiswal, M Aquib - Am J Pharm Tech Res, 2016

Surface receptor‐mediated targeted drug delivery systems for enhanced cancer treatment: A state‐of‐the‐art review

S Kunjiappan, P Pavadai, S Vellaichamy… - Drug Development …, 2021 - Wiley Online Library
Enhanced cancer treatment remains as one of the focused areas for researchers around the
world. Hence, the progress in this direction will be a challenge and an opportunity in, inter …