Membrane injury facilitated the fixation of calcium oxalate crystals and subsequent growth
into kidney stones. Oxalate-induced membrane injury was mediated by lipid peroxidation …

In a previous study we demonstrated that oxalate induced free radical injury can promote
calcium oxalate stone formation. In the present study, we tested whether the antioxidants …

PURPOSE: To determine if lipid peroxidation plays a role in renal injury associated with
experimental nephrolithiasis. MATERIALS AND METHODS: Hyperoxaluria was produced in …

OBJECTIVES: To determine whether lipid peroxidation plays a role in patients with calcium
oxalate kidney stones and to determine the correlation of lipid peroxidation with tubular …

OBJECTIVE To determine whether vitamin E prevents hyperoxaluria‐induced stone
formation, using a new animal model of calcium oxalate stone disease, as our previous in …

Calcium oxalate (CaOx) kidney stones are formed attached to Randall's plaques (RPs) or
Randall's plugs. Mechanisms involved in the formation and growth are poorly understood. It …

Crystal modulators play a significant role in the formation of calcium oxalate stone disease.
When renal cells are subjected to oxalate stress, the loss in cell integrity leads to exposure …

Renal cellular exposure to oxalate (Ox) and/or CaOx crystals leads to the production of
reactive oxygen species (ROS), development of oxidative stress followed by injury and …

The effects of free radicals on the development of crystals attached to the living epithelium
have been studied using an experimental model that enables close simulation of the …

Oxalate, one of the major constituents of renal stones is known to induce free radicals which
damage the renal membrane. Damaged epithelia might act as nidi for stone formation …