microRNA and the pathogenesis of ovarian cancer-a new horizon for molecular diagnostics and treatment?

JD Kuhlmann, J Rasch, P Wimberger… - Clinical Chemistry & …, 2012 - search.ebscohost.com
Ovarian cancer is the leading cause of death among gynecologic malignancies and despite
advances in treatment, more than 50% of all patients will experience recurrence, resulting in …

A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer

X Hu, DM Macdonald, PC Huettner, Z Feng… - Gynecologic …, 2009 - Elsevier
OBJECTIVE: Ovarian cancer is one of the most deadly human cancers, resulting in over
15,000 deaths in the US each year. A reliable method that could predict disease outcome …

[HTML][HTML] Characterization of microRNA expression in serous ovarian carcinoma

Y Li, L Yao, F Liu, J Hong, L Chen… - International …, 2014 - spandidos-publications.com
Serous ovarian cancer is a major gynecologic malignancy with a poor 5‑year survival rate.
However, little is known regarding the behavior and genetics of ovarian tumorigenesis …

[HTML][HTML] MicroRNA expression in ovarian carcinoma and its correlation with clinicopathological features

H Lee, CS Park, G Deftereos, J Morihara… - World journal of surgical …, 2012 - Springer
Background MicroRNA (miRNA) expression is known to be deregulated in ovarian
carcinomas. However, limited data is available about the miRNA expression pattern for the …

[HTML][HTML] The role of miRNA in ovarian cancer: an overview

L Zhao, X Liang, L Wang, X Zhang - Reproductive sciences, 2022 - Springer
Ovarian cancer (OC) is a highly malignant disease that seriously threatens women's health
and poses challenges for clinicians. MicroRNAs (miRNAs) have recently been intensively …

[HTML][HTML] MicroRNA and ovarian cancer

DC Corney, AY Nikitin - Histology and histopathology, 2008 - ncbi.nlm.nih.gov
Ovarian cancer remains a leading cause of morbidity and mortality, with little change in
survival rates over the past 30 years. Research in the molecular biology underlying the …

[HTML][HTML] Role of microRNAs as clinical cancer biomarkers for ovarian cancer: a short overview

CE Staicu, DV Predescu, CM Rusu, BM Radu… - Cells, 2020 - mdpi.com
Ovarian cancer has the highest mortality rate among gynecological cancers. Early clinical
signs are missing and there is an urgent need to establish early diagnosis biomarkers …

MicroRNAs that underlie ovarian cancer development and response to chemotherapy

S Cui, T Boren, G Chan, M Indermauer1, HK Dressman… - Cancer Research, 2007 - AACR
Abstract 4514 Introduction: MicroRNAs (miRNAs) are non-protein-coding, endogenous,
small RNAs that can bind complementary mRNA to modulate gene expression and protein …

miRNA profiling along tumour progression in ovarian carcinoma

O Vaksman, HT Stavnes, J Kærn… - Journal of cellular …, 2011 - Wiley Online Library
MicroRNAs (miRNAs) are small non‐coding RNAs that exert a regulatory effect post‐
transcriptionally by binding target mRNAs and inhibiting gene translation. miRNA …

[PDF][PDF] The role of microRNAs in the tumorigenesis of ovarian cancer

G Di Leva, CM Croce - Frontiers in oncology, 2013 - frontiersin.org
Epithelial ovarian cancer (EOC) is a complex disease, with multiple histological subtypes
recognized. There have been major advances in the understanding of the cellular and …