Plasma miRNAs as diagnostic and prognostic biomarkers for ovarian cancer

H Zheng, L Zhang, Y Zhao, D Yang, F Song, Y Wen… - PloS one, 2013 - journals.plos.org
Background Most (70%) epithelial ovarian cancers (EOCs) are diagnosed late. Non-invasive
biomarkers that facilitate disease detection and predict outcome are needed. The …

Evaluation of prognostic and predictive significance of circulating microRNAs in ovarian cancer patients

AR Halvorsen, G Kristensen, A Embleton… - Disease …, 2017 - Wiley Online Library
Ovarian cancer patients are recognized with poor prognosis. This study aimed to identify
microRNAs in plasma for predicting response to treatment and outcome. We have …

MicroRNA-9 promotes tumorigenesis and mediates sensitivity to cisplatin in primary epithelial ovarian cancer cells

HM Zhao, W Wei, YH Sun, JH Gao, Q Wang, JH Zheng - Tumor Biology, 2015 - Springer
MicroRNAs play critical roles in regulating tumor occurrence and drug sensitivity in ovarian
cancers. This study aimed to investigate the key members of MicroRNAs (miRNAs) involved …

The miR-200 family: versatile players in epithelial ovarian cancer

GG Muralidhar, MV Barbolina - International journal of molecular sciences, 2015 - mdpi.com
The role of microRNAs (miRNAs or miRs) in the pathology of epithelial ovarian cancer
(EOC) has been extensively studied. Many miRNAs differentially expressed in EOC as …

[HTML][HTML] Role of MicroRNAs in carcinogenesis that potential for biomarker of endometrial cancer

MS Djati, M Rifa'i - Annals of medicine and surgery, 2016 - Elsevier
The non-invasive diagnostic tool for early detection of endometrial cancer still limited. The
etiology of this disease is believed to be associated with disharmony hormone production …

[HTML][HTML] Modulation of chemoresponsiveness to platinum-based agents by microRNAs in cancer

X Yu, H Zheng, MTV Chan, WKK Wu - American Journal of Cancer …, 2017 - ncbi.nlm.nih.gov
Ovarian cancer accounts for the highest mortality among all gynecologic cancers.
Cytoreductive surgery followed by chemotherapy with a platinum-based agent (cisplatin or …

microRNA‐based diagnostic and therapeutic applications in cancer medicine

LF Sempere, AS Azmi, A Moore - Wiley Interdisciplinary …, 2021 - Wiley Online Library
It has been almost two decades since the first link between microRNAs and cancer was
established. In the ensuing years, this abundant class of short noncoding regulatory RNAs …

The circulating microRNA‑200 family in whole blood are potential biomarkers for high‑grade serous epithelial ovarian cancer

A Pendlebury, NJ Hannan, N Binder… - Biomedical …, 2017 - spandidos-publications.com
Epithelial ovarian cancer (EOC) is the leading cause of mortality with regard to
gynaecological cancer. There is no effective biomarker and therefore prognosis is poor as …

MicroRNA Gene Expression Signature Driven by miR-9 Overexpression in Ovarian Clear Cell Carcinoma

N Yanaihara, Y Noguchi, M Saito, M Takenaka… - PloS one, 2016 - journals.plos.org
Previous studies have identified microRNA (miRNA) involvement in human cancers. This
study aimed to elucidate potential clinical and biological associations of ovarian cancer …

Regulation of metastasis by microRNAs in ovarian cancer

Y Wang, S Kim, I Kim - Frontiers in Oncology, 2014 - frontiersin.org
Ovarian cancer (OC) is the second most common and the most fatal gynecologic cancer in
the United States. Over the last decade, various targeted therapeutics have been introduced …