Genomic islands of Pseudomonas aeruginosa

SE Battle, J Rello, AR Hauser - FEMS microbiology letters, 2009 - academic.oup.com
Key to Pseudomonas aeruginosa's ability to thrive in a diversity of niches is the presence of
numerous genomic islands that confer adaptive traits upon individual strains. We reasoned …

Hybrid Pathogenicity Island PAGI-5 Contributes to the Highly Virulent Phenotype of a Pseudomonas aeruginosa Isolate in Mammals

SE Battle, F Meyer, J Rello, VL Kung… - Journal of …, 2008 - Am Soc Microbiol
Most known virulence determinants of Pseudomonas aeruginosa are remarkably conserved
in this bacterium's core genome, yet individual strains differ significantly in virulence. One …

The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes

J He, RL Baldini, E Déziel, M Saucier… - Proceedings of the …, 2004 - National Acad Sciences
The ubiquitous bacterium Pseudomonas aeruginosa is the quintessential opportunistic
pathogen. Certain isolates infect a broad range of host organisms, from plants to humans …

Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial

DG Lee, JM Urbach, G Wu, NT Liberati, RL Feinbaum… - Genome biology, 2006 - Springer
Background Pseudomonas aeruginosa is a ubiquitous environmental bacterium and an
important opportunistic human pathogen. Generally, the acquisition of genes in the form of …

Genomic complexity and plasticity ensure Pseudomonas success

KP Rumbaugh - FEMS Microbiology Letters, 2014 - academic.oup.com
The first Pseudomonas genome was sequenced in 2000, and at 6.3 million base pairs, it
was, at the time, the largest bacterial genome ever sequenced (Stover et al., 2000). Not …

Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa

C Winstanley, MGI Langille, JL Fothergill… - Genome …, 2009 - genome.cshlp.org
Pseudomonas aeruginosa isolates have a highly conserved core genome representing up
to 90% of the total genomic sequence with additional variable accessory genes, many of …

The Accessory Genome of Pseudomonas aeruginosa

VL Kung, EA Ozer, AR Hauser - Microbiology and molecular …, 2010 - Am Soc Microbiol
Pseudomonas aeruginosa strains exhibit significant variability in pathogenicity and
ecological flexibility. Such interstrain differences reflect the dynamic nature of the P …

Pseudomonas aeruginosa Genomic Structure and Diversity

J Klockgether, N Cramer, L Wiehlmann… - Frontiers in …, 2011 - frontiersin.org
The Pseudomonas aeruginosa genome (G+ C content 65–67%, size 5.5–7 Mbp) is made up
of a single circular chromosome and a variable number of plasmids. Sequencing of …

Identification of a Genomic Island Present in the Majority of Pathogenic Isolates of Pseudomonas aeruginosa

X Liang, XQT Pham, MV Olson, S Lory - Journal of bacteriology, 2001 - Am Soc Microbiol
Pseudomonas aeruginosa, a ubiquitous gram-negative bacterium, is capable of colonizing a
wide range of environmental niches and can also cause serious infections in humans. In …

Conservation of genome content and virulence determinants among clinical and environmental isolates of Pseudomonas aeruginosa

MC Wolfgang, BR Kulasekara… - Proceedings of the …, 2003 - National Acad Sciences
Pseudomonas aeruginosa is a ubiquitous environmental bacterium capable of causing a
variety of life-threatening human infections. The genetic basis for preferential infection of …