Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect?
Data from basic science experiments is overwhelmingly supportive of the causal role of
immune‐inflammatory response (s) at the core of atherosclerosis, and therefore, the …
immune‐inflammatory response (s) at the core of atherosclerosis, and therefore, the …
Immunity, atherosclerosis and cardiovascular disease
J Frostegård - BMC medicine, 2013 - Springer
Atherosclerosis, the major cause of cardiovascular disease (CVD), is a chronic inflammatory
condition with immune competent cells in lesions producing mainly pro-inflammatory …
condition with immune competent cells in lesions producing mainly pro-inflammatory …
[HTML][HTML] Anti-inflammatory and immune-modulatory therapies for preventing atherosclerotic cardiovascular disease
T Yamashita, N Sasaki, K Kasahara, K Hirata - Journal of cardiology, 2015 - Elsevier
Atherosclerosis is believed to be a chronic inflammation of the arterial wall and various
immune cells of innate and adaptive immunity involves in the pathogenesis of …
immune cells of innate and adaptive immunity involves in the pathogenesis of …
Immune-mediated mechanisms of atherosclerosis and implications for the clinic
Introduction: A large body of evidence supports the inflammatory hypothesis of
atherosclerosis, and both innate and adaptive immune responses play important roles in all …
atherosclerosis, and both innate and adaptive immune responses play important roles in all …
Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?
SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
Immune and smooth muscle cells interactions in atherosclerosis: how to target a breaking bad dialogue?
D Ramel, S Gayral, MK Sarthou, N Augé… - Frontiers in …, 2019 - frontiersin.org
Inflammation is a well-known pathophysiological factor of atherosclerosis but its therapeutic
targeting has long been ignored. However, recent advances in the understanding of the …
targeting has long been ignored. However, recent advances in the understanding of the …
Inflammation as a therapeutic target in atherosclerosis
MT Nguyen, S Fernando, N Schwarz, JTM Tan… - Journal of clinical …, 2019 - mdpi.com
Atherosclerotic coronary artery disease (CAD) results from build-up of cholesterol-rich
plaques in the walls of the coronary arteries and is a leading cause of death. Inflammation is …
plaques in the walls of the coronary arteries and is a leading cause of death. Inflammation is …
Targeting inflammation in atherosclerosis—from experimental insights to the clinic
O Soehnlein, P Libby - Nature reviews Drug discovery, 2021 - nature.com
Atherosclerosis, a dominant and growing cause of death and disability worldwide, involves
inflammation from its inception to the emergence of complications. Targeting inflammatory …
inflammation from its inception to the emergence of complications. Targeting inflammatory …
Inflammation modulation and cardiovascular disease prevention
Z Awan, J Genest - European Journal of Preventive Cardiology, 2015 - academic.oup.com
Heart disease and stroke represent the major burden of health worldwide and account for a
staggering 17 million deaths yearly. This pandemic is, in great part preventable through …
staggering 17 million deaths yearly. This pandemic is, in great part preventable through …
[HTML][HTML] Critical roles of inflammation in atherosclerosis
J Moriya - Journal of cardiology, 2019 - Elsevier
There is accumulating evidence that vascular inflammation plays critical roles in
pathophysiology of atherosclerosis. It is widely accepted that both innate and adaptive …
pathophysiology of atherosclerosis. It is widely accepted that both innate and adaptive …