Few virulence determinants of Helicobacter pylori have been tested in vivo. We conducted
this study to establish an animal model for their screening. Six-week-old male Mongolian …

Since it has been shown that Helicobacter hepaticus causes both chronic hepatitis and
hepatocellular carcinoma (HCC) in mice, it is suggested that differences in the progression …

The ability of Helicobacter pylori to tolerate bile is likely to be important for its colonization
and survival in the gastrointestinal tract of humans. As bile can be acidified after reflux into …

ABSTRACT A novel PCR restriction analysis method using the RNA polymerase β-subunit-
coding gene (rpoB) was employed to both detect and identify Helicobacter pylori in biopsy …

Background & Aims: Helicobacter pylori interact with epithelial cells resulting in activation of
cellular signaling pathways leading to an inflammatory response. The pattern and timing of …

Background It has been documented that Helicobacter hepaticus (H hepaticus) infection is
linked to chronic hepatitis and liver cancer. However, our understanding of the molecular …

Background Several studies have reported the presence of H. pylori in individuals with
hepatobiliary diseases, but in vitro and in vivo studies are still needed. Here, we determined …

AIM: To study the effect of IL-10 on the expression of growth factors-transforming growth
factor-β1 (TGF-β1), epidermal growth factor (EGF), hepatocyte growth factor (HGF) and …

The present study was to study the hepatoprotective effects of phloridzin (PHL) on hepatic
fibrosis induced by carbon tetrachloride (CCl4) in rats, on the basis of this investigation, the …

Background Chronic viral hepatitis is linked to fibrotic liver injury that can progress to liver
cirrhosis with its associated complications. Recent evidence suggests a role of senescence …