Bacterial site‐specific DNA inversion systems

RC Johnson - Mobile DNA II, 2007 - Wiley Online Library
Specialized recombination reactions involving DNA inversions have evolved as a
mechanism to generate genetic diversity within a population. They often function to preadapt …

DNA inversions in phages and bacteria

P Van de Putte, N Goosen - Trends in Genetics, 1992 - cell.com
The inversion enzymes of the FimI system of E. coli also belong to the integrase family.
Since the biological function of this genetic switch resembles that promoted by the members …

Identification of two functional regions in Fis: the N‐terminus is required to promote Hin‐mediated DNA inversion but not lambda excision.

R Osuna, SE Finkel, RC Johnson - The EMBO Journal, 1991 - embopress.org
The Fis protein of E. coli binds to a recombinational enhancer sequence that is required to
stimulate Hin‐mediated DNA inversion. Fis is also required for efficient lambda prophase …

Location, degree, and direction of DNA bending associated with the Hin recombinational enhancer sequence and Fis-enhancer complex

D Perkins-Balding, DP Dias… - Journal of bacteriology, 1997 - Am Soc Microbiol
The Fis protein of Escherichia coli and Salmonella typhimurium stimulates several site-
specific DNA recombination reactions, as well as transcription of a number of genes. Fis …

Fis binding to the recombinational enhancer of the Hin DNA inversion system.

MF Bruist, AC Glasgow, RC Johnson… - Genes & …, 1987 - genesdev.cshlp.org
The recombinational enhancer of the Hin inversion system in Salmonella stimulates
recombination in vitro 150-fold in the presence of the Escherichia coli host factor Fis. To gain …

DNA Supercoiling and the Lrp Protein Determine the Directionality of fim Switch DNA Inversion in Escherichia coli K-12

A Kelly, C Conway, T Ó Cróinín, SGJ Smith… - Journal of …, 2006 - Am Soc Microbiol
Site-specific recombinases of the integrase family usually require cofactors to impart
directionality in the recombination reactions that they catalyze. The FimB integrase inverts …

Integration host factor is required for the DNA inversion that controls phase variation in Escherichia coli.

BI Eisenstein, DS Sweet, V Vaughn… - Proceedings of the …, 1987 - National Acad Sciences
The on-and-off expression (phase variation) of type 1 fimbriae, encoded by fimA, in
Escherichia coli is controlled by the inversion of a promoter-containing 314-base-pair DNA …

Site‐specific DNA inversion by serine recombinases

RC Johnson - Mobile DNA III, 2015 - Wiley Online Library
Reversible site‐specific inversions of DNA segments occur within the genomes of many
bacteria and their phages. These reactions are catalyzed by a dedicated recombinase and …

The N-terminal part of the E.Coli DNA binding protein FIS is essential for stimulating site-specific DNA inversion but is not required for specific DNA …

C Koch, O Ninnemann, H Fuss… - Nucleic acids …, 1991 - academic.oup.com
FIS protein is involved in several different cellular processes stimulating site-specific
recombination in phages Mu and λ as well as transcription of stable RNA operons in E. coli …

Topological analysis of Hin‐catalysed DNA recombination in vivo and in vitro

SK Merickel, RC Johnson - Molecular microbiology, 2004 - Wiley Online Library
In vitro studies have demonstrated that Hin‐catalysed site‐specific DNA inversion occurs
within a tripartite invertasome complex assembled at a branch on a supercoiled DNA …