Utilizing the gut microbiome in decompensated cirrhosis and acute-on-chronic liver failure

J Trebicka, P Bork, A Krag, M Arumugam - … reviews Gastroenterology & …, 2021 - nature.com
The human gut microbiome has emerged as a major player in human health and disease.
The liver, as the first organ to encounter microbial products that cross the gut epithelial …

[HTML][HTML] Gut microbiome-based therapeutics in liver cirrhosis: basic consideration for the next step

H Fukui - Journal of Clinical and Translational Hepatology, 2017 - ncbi.nlm.nih.gov
Infections account for significant morbidity and mortality in liver cirrhosis and most are
related to the gut microbiome. Fecal dysbiosis, characterized by an overgrowth of potentially …

Altered microbiome in patients with cirrhosis and complications

C Acharya, JS Bajaj - Clinical Gastroenterology and Hepatology, 2019 - Elsevier
In patients with cirrhosis, the gut microbiome are affected by multiple gut and systemic
alterations. These changes lead to dysbiosis in the microbiota of different parts of the body …

[HTML][HTML] The microbiota in cirrhosis and its role in hepatic decompensation

J Trebicka, J Macnaughtan, B Schnabl… - Journal of …, 2021 - Elsevier
Cirrhosis–the common end-stage of chronic liver disease–is associated with a cascade of
events, of which intestinal bacterial overgrowth and dysbiosis are central. Bacterial toxins …

Gut–liver axis: how do gut bacteria influence the liver?

PC Konturek, IA Harsch, K Konturek, M Schink… - Medical …, 2018 - mdpi.com
Chronic liver diseases are a major cause of morbidity and mortality worldwide. Recently, gut
dysbiosis was identified as an important factor in the pathogenesis of liver diseases. The …

Gut microbiome and liver diseases

H Tilg, PD Cani, EA Mayer - Gut, 2016 - gut.bmj.com
The gut microbiota has recently evolved as a new important player in the pathophysiology of
many intestinal and extraintestinal diseases. The liver is the organ which is in closest contact …

Gut microbiome and liver disease

NS Betrapally, PM Gillevet, JS Bajaj - Translational Research, 2017 - Elsevier
Gut microbiota changes are important in determining the occurrence and progression of
chronic liver disease related to alcohol, nonalcoholic fatty liver disease, and cirrhosis …

[HTML][HTML] Alterations in gut microbiome in cirrhosis as assessed by quantitative metagenomics: relationship with acute-on-chronic liver failure and prognosis

C Solé, S Guilly, K Da Silva, M Llopis, E Le-Chatelier… - Gastroenterology, 2021 - Elsevier
Background and Aims Cirrhosis is associated with changes in gut microbiome composition.
Although acute-on-chronic liver failure (ACLF) is the most severe clinical stage of cirrhosis …

[HTML][HTML] Role of gut microbiota in liver disease

SAM Albhaisi, JS Bajaj… - American Journal of …, 2020 - journals.physiology.org
The gut microbiome is the natural intestinal inhabitant that has been recognized recently as
a major player in the maintenance of human health and the pathophysiology of many …

Gut dysbiosis in acute‐on‐chronic liver failure and its predictive value for mortality

Y Chen, J Guo, G Qian, D Fang, D Shi… - Journal of …, 2015 - Wiley Online Library
Background Bacterial translocation from the gut plays an important role in the
pathophysiology of acute‐on‐chronic liver failure (ACLF). However, gut dysbiosis in ACLF …