Proliferation and metastasis are significantly malignant characteristics of human lung
cancer, but the underlying molecular mechanisms are poorly understood. Chromobox 4 …

Dysregulation of polycomb group (PcG) proteins that mediate epigenetic gene silencing
contributes to tumorigenesis. As core components of the polycomb repressive complex 1 …

Chromobox protein homolog 7 (CBX7) is a member of the Chromobox protein family and
participates in the formation of the polycomb repressive complex 1 (PRC1). In cells, CBX7 …

The chromobox protein homolog 7 (CBX7), one member of the polycomb group family, has
been characterized mainly to play a tumor-suppressive role in human malignant neoplasias …

Background We have previously shown that the expression of CBX7 is drastically decreased
in several human carcinomas and that its expression progressively decreases with the …

Purpose Hepatocellular carcinoma (HCC) is the most common malignant tumor worldwide
with high morbidity and mortality rates. We aimed to examine the expression of chromobox 6 …

Chromobox (CBX) family members are vital epigenetic regulators that repress the
transcription of target genes through chromatin modification. Several studies have …

Aberrant chromobox (CBX) family protein expression has been reported in a variety of
human malignancies. However, the role of CBX6 in hepatocellular carcinoma (HCC) …

Metastasis is associated with poor prognosis in cancer and is a multistep process that
includes invasion and migration. Several epigenetic factors are involved in this process …

Polycomb group family is a class of proteins that have important roles in both physiological
and pathological processes, and its family member Chromobox homolog 8 (CBX8) regulates …