Since the first description of the canonical B-form DNA double helix, it has been suggested
that alternative DNA, DNA–RNA, and RNA structures exist and act as functional genomic …

DNA structure is a critical element in determining its function. The DNA molecule is capable
of adopting a variety of non-canonical structures, including three-stranded (ie triplex) …

Triplexes are noncanonical DNA structures, which are functionally associated with
regulation of gene expression through ncRNA targeting to chromatin. Based on the rules of …

The ability of double-stranded DNA to form a triple-helical structure by hydrogen bonding
with a third strand is well established, but the biological functions of these structures remain …

Recent studies suggest noncoding RNAs interact with genomic DNA, forming an RNA• DNA–
DNA triple helix that regulates gene expression. However, base triplet composition of …

Triplex nanostructures can be formed in vitro in the promoter region of DNA templates, and it
is commonly accepted that these assemblies inhibit the transcription of the downstream …

RNA can directly bind to purine-rich DNA via Hoogsteen base pairing, forming a DNA: RNA
triple helical structure that anchors the RNA to specific sequences and allows guiding of …

The right-handed double-helical B-form structure (B-form duplex) has been widely
recognized as the canonical structure of nucleic acids since it was first proposed by James …

The ability of RNA to form sophisticated secondary and tertiary structures enables it to
perform a wide variety of cellular functions. One tertiary structure, the RNA triple helix, was …

Nowadays, decades after the discovery of the right‐handed B form of DNA, it is well known
that nucleic acids have great conformational flexibility, exhibiting a large degree of variation …