Apoptosis: Activate NF-κB or die?: Current Biology Skip to Main Content Advertisement Current
Biology This journal offers authors two options (open access or subscription) to publish research …

The transcription factor nuclear factor κB (NF-κB) is a pleiotropic protein complex that is
activated from a sequestered, cytoplasmic form by pro-inflammatory extracellular signals …

During their lifetime, cells encounter many life or death situations that challenge their very
own existence. Their survival depends on the interplay within a complex yet precisely …

Apoptosis is a mode of cell death that plays an important role in both pathological and
physiological processes. Research during the last decade has delineated the entire …

The nuclear factor-kappaB (NF-κB) transcription factors have emerged as major regulators
of programmed cell death (PCD) whether via apoptosis or necrosis. In this context, NF-κB's …

To test whether the behaviour of transcription factor NF‐κB as a promoter or antagonist of
apoptosis depends on the apoptotic stimulus, we determined the influence of NF‐κB on cell …

Recently NF-κB has been shown to have both proapoptotic and antiapoptotic functions. In T
cell hybridomas, both T cell activators and glucocorticoids induce apoptosis. Here we show …

The process of apoptosis is used to eliminate unwanted cells from a wide variety of
organisms. Various extracellular signals, often converging in common intracellular …

Recent progress in the identification and functional analysis of protein kinases and adapter
molecules that lead to activation of NF-κB family transcription factors has lead to a quite …

It is not clear why on treatment with certain killer cytokines or chemotherapeutic agents,
some cells undergo apoptosis while others do not. The delineation of sensitivity/resistance …