Understanding the molecular epidemiology of tuberculosis (TB) and mutations in genes
associated with drug resistance may contribute to the development of appropriate …

Purpose The emergence of isoniazid-resistant tuberculosis (HR-TB) is a global public health
problem, causing treatment failure and high mortality rates. This study aimed to determine …

OBJECTIVE: To evaluate the distribution of the Mycobacterium tuberculosis Beijing
genotype and the association of the genotype with drug-resistant M. tuberculosis strains in …

Background With the widespread use of rifampicin and isoniazid, bacterial resistance has
become a growing problem. Additionally, the lack of relevant baseline information for the …

Background The aim of this study was to identify mutations of r poB, katG, inhA and ahp-
genes associated Mycobacterium tuberculosis resistance to rifampicin (RIF) and isoniazid …

Molecular diagnostic assays, with their ability to rapidly detect resistance-associated
mutations in bacterial genes, are promising technologies to control the spread of drug …

OBJECTIVES: A population-based study was performed to characterise the genotype and
phenotype of drug-resistant tuberculosis (TB) in the year 2004–2005 in two Chinese rural …

Objective The aim was to analyze genetic mutations in the rpoB gene of rifampin-resistant
Mycobacterium tuberculosis isolates (RIFR-MTB) from Zhejiang, China. Methods We …

Background and Objective: Tuberculosis (TB) is a devastating infectious disease causing
high mortality and morbidity worldwide. The most serious threat related to tuberculosis …

Objective To study the genotypes of representative Mycobacterium tuberculosis (M.
tuberculosis) strains from China with spacer oligonucleotide typing (spoligotyping), and to …