Complex regional pain syndrome (CRPS) is a disorder that involves abnormal inflammation
and nerve dysfunction frequently resistant to a broad range of treatments. Peripheral nerve …

Although pregabalin has been shown to have preclinical and clinical efficacy in neuropathic
pain, the mechanism of its antinociceptive action is still unknown in other pain states. This …

Abstract Ethnopharmacological relevance Yuanhu Zhitong Prescription (YZP) is a well-
known traditional Chinese medicine (TCM) formula for neuropathic pain (NP) therapy with a …

In this study, we attempted to identify the possible antinociceptive action of aqueous extract
(AE) obtained from roots of Physalis angulata, known in Brazil as “Camapu”, used to treat …

BACKGROUND: Shakuyakukanzoto (SKT) has been shown to modulate nociception in
streptozotocin-induced diabetic mice via selective activation of the descending …

Background Evidence is building steadily on the effectiveness of acupuncture therapy in
pain relief and repeated acupuncture-induced pain relief is accompanied by improvement of …

Bone cancer pain (BCP) is one of the most common and severe complications in patients
suffering from primary bone cancer or metastatic bone cancer such as breast, prostate, or …

Background/Purpose In a recent study, we found that baicalin exhibited a potent analgesic
effect on carrageenan-evoked thermal hyperalgesia. The underlining mechanisms may be …

Background: Arthritis is an inflammatory disease that affects the joints. Patients suffering
from chronic pain are anxious, which contributes to reducing the quality of life. The …

Currently, the clinical management of visceral pain remains unsatisfactory for many patients
suffering from this disease. While preliminary animal studies have suggested the …