Acute hepatotoxicity from amiodarone

C Tosetti, M Ongari, A Evangelisti, R Lolli… - Minerva Medica, 1995 - europepmc.org
The functional and histological liver alterations induced by amiodarone treatment have been
well known for some time and often consist in isolated increases in transaminase levels …

“Torsade de pointes” during amiodarone infusion in a cirrhotic woman with a prolonged QT interval

A Di Micoli, A Zambruni, E Bracci, B Benazzi… - Digestive and Liver …, 2009 - Elsevier
We describe an interesting case of a woman with decompensated cirrhosis, ischaemic heart
disease and prolonged QT interval, who developed a new-onset atrial fibrillation. During …

Can pancreatitis be associated with amiodarone hepatotoxicity?

SV Sastri, AA Diaz-Arias… - Journal of clinical …, 1990 - journals.lww.com
We report a patient with classical features of amiodarone hepatotoxicity who died of
progressive liver failure. Throughout the course of his illness, he had epigastric pain …

Severe intrahepatic cholestasis caused by amiodarone toxicity after withdrawal of the drug: a case report and review of the literature

CC Chang, M Petrelli… - … of Pathology and …, 1999 - meridian.allenpress.com
Cholestasis has been reported as a rare presentation among patients with severe liver injury
secondary to amiodarone hepatic toxicity. We report an unusual case of amiodarone …

Chronic liver disease after low daily doses of amiodarone: report of three cases

G Babany, A Mallat, ES Zafrani, MFSM Girardin… - Journal of …, 1986 - Elsevier
A few cases of alcohol-like chronic liver disease have recently been described in patients on
high daily doses of amiodarone (400–600 mg) for 5–24 months. We report here 3 cases in …

Acute hepatitis induced by parenteral amiodarone

SA Gregory, JB Webster, GD Chapman - The American journal of …, 2002 - amjmed.com
Hepatic dysfunction, most commonly an elevation of aminotransferases, develops in 15% to
40% of patients receiving amiodarone (1). However, acute hepatitis induced by parenteral …

Rapidly fatal acute amiodarone hepatitis occurring in the context of multiple organ failure

RJ MacFadyen, TJ Palmer… - International …, 2003 - internationaljournalofcardiology.com
Amiodarone remains the agent of choice for the 80 mmHg and clinical and radiological
evidence of management of atrial fibrillation in unstable patients fluid overload. He was …

Probable early acute hepatitis with parenteral amiodarone

J Lupon‐Rosés, R SimÓa‐Canonge… - Clinical …, 1986 - Wiley Online Library
A patient with acute changes suggesting acute hepatitis after parenteral amiodarone
administration is described. A 77‐year‐old man with previous myocardial infarction was …

Amiodarone exposure during modest inflammation induces idiosyncrasy-like liver injury in rats: role of tumor necrosis factor-alpha

J Lu, AD Jones, JR Harkema, RA Roth… - Toxicological …, 2012 - academic.oup.com
Abstract Amiodarone [2-butyl-3-(3′, 5′-diiodo-4'α-diethylaminoethoxybenzoyl)-
benzofuran](AMD), a class III antiarrhythmic drug, is known to cause idiosyncratic …

Acute amiodarone-induced hepatitis.

N Kalantzis, P Gabriel, J Mouzas, D Tiniakos… - Hepato …, 1991 - europepmc.org
Two fatal cases of amiodarone-induced acute, confluent, necrotic hepatitis are described.
The patients, aged 28 and 60, had received a high loading dose of amiodarone. After the …