Drug‐induced liver injury (DILI) is the most frequent cause of post‐marketing warnings and
withdrawals. Amiodarone (AMD), an antiarrhythmic, presents a risk of liver injury in humans …

Two fatal cases of amiodarone-induced acute, confluent, necrotic hepatitis are described.
The patients, aged 28 and 60, had received a high loading dose of amiodarone. After the …

The aim of this work was to compare hepatocellular toxicity and pharmacological activity of
amiodarone (2-n-butyl-3-[3, 5 diiodo-4-diethylaminoethoxybenzoyl]-benzofuran; B2-O-Et-N …

Amiodarone (AMD), a class III antiarrhythmic drug, causes idiosyncratic hepatotoxicity in
human patients. We demonstrated previously that tumor necrosis factor-alpha (TNF-α) plays …

Acute burn and trauma patients have a higher frequency of cardiac arrhythmias than would
be expected for noncardiac-hospitalized patients. Amiodarone is an effective, commonly …

DISCUSSION Amiodarone is becoming the drug of choice in the treatment of atrial
fibrillation, particularly in the postsurgical setting (1, 2). However, it is associated with many …

Nonalcoholic steatosis/steatohepatitis is the most common cause for abnormal liver
chemistries. Apart from metabolic syndrome, drugs may also lead to development of …

Five patients had amiodarone hepatotoxicity detected on routine biochemical monitoring.
Symptoms attributable to hepatotoxicity were minimal or absent; reversible hepatomegaly …

Objetivo: Informar un caso de hepatotoxicidad fatal asociado al uso crónico de amiodarona
oral. Resumen Del Caso: En 1992 un paciente de 64 años requirió el uso de amiodarona …