Defects of the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) protein
affect the homeostasis of chloride, bicarbonate, sodium, and water in the airway surface …

Understanding the development of lung disease in cystic fibrosis (CF) has been a sought
after goal for several decades. With the cloning of the CF transmembrane conductance …

Cystic Fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene
encoding for the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein …

Cystic fibrosis (CF) is an autosomal recessive disease that is caused by mutations in the
cystic fibrosis conductance regulator (CFTR) gene and usually presents with multiorgan …

Cystic fibrosis (CF) is an inherited disorder caused by mutations in the gene encoding for the
cystic fibrosis transmembrane conductance regulator (CFTR) protein, an ATP-gated chloride …

Cystic fibrosis (CF) is a common, life-threatening, multisystemic, autosomal recessive
disorder. In the last few years, giant steps have been made with regard to the understanding …

ALTHOUGH IT HAS BEEN 17 YEARS since the identification of the cystic fibrosis
transmembrane ion receptor (CFTR) gene and protein, it remains enigmatic how …

The cystic fibrosis (CF) transmembrane conductance regulator (CFTR) is a cAMP-activated
anion channel, primarily expressed in ciliated epithelial cells that have an endoluminal …

Chronic obstructive lung disease starting in the first months of life remains the major cause
of morbidity and mortality in patients with cystic fibrosis (CF). The discovery of the cystic …

The cystic fibrosis transmembrane conductance regulator (CFTR) is a crucial ion channel for
transport of chloride and bicarbonate anions. Functional roles of CFTR have been identified …