A Pilot Trial of Platelets Stored Cold versus at Room Temperature for Complex Cardiothoracic Surgery
G Strandenes, J Sivertsen, CK Bjerkvig, TK Fosse… - …, 2020 - pubs.asahq.org
Background This pilot trial focused on feasibility and safety to provide preliminary data to
evaluate the hemostatic potential of cold-stored platelets (2° to 6° C) compared with …
evaluate the hemostatic potential of cold-stored platelets (2° to 6° C) compared with …
A randomized, controlled pilot clinical trial of cryopreserved platelets for perioperative surgical bleeding: the CLIP‐I trial (Editorial, p. 2759)
BACKGROUND Cryopreservation extends platelet (PLT) shelf life from 5 to 7 days to 2 to 4
years. However, only 73 patients have been transfused cryopreserved PLTs in published …
years. However, only 73 patients have been transfused cryopreserved PLTs in published …
[HTML][HTML] Comparison of the effects of transfusions of cryopreserved and liquid-preserved platelets on hemostasis and blood loss after cardiopulmonary bypass
SF Khuri, N Healey, H MacGregor, MR Barnard… - The Journal of thoracic …, 1999 - Elsevier
Objective: The aim of the study was to compare the clinical effects and hemostatic efficiency
of transfusions of platelets preserved in the frozen state for as long as 2 years with …
of transfusions of platelets preserved in the frozen state for as long as 2 years with …
Cold-stored platelets: review of studies in humans
Although numerous reviews and editorials have been published about the biologic features
of platelets exposed to cold temperature and their in vitro function, none has focused on the …
of platelets exposed to cold temperature and their in vitro function, none has focused on the …
Maximising platelet availability by delaying cold storage
B Wood, L Johnson, RA Hyland, DC Marks - Vox sanguinis, 2018 - Wiley Online Library
Background and Objectives Cold‐stored platelets may be an alternative to conventional
room temperature (RT) storage. However, cold‐stored platelets are cleared more rapidly …
room temperature (RT) storage. However, cold‐stored platelets are cleared more rapidly …
Cold-stored platelets: A product with function optimized for hemorrhage control
KM Reddoch-Cardenas, JA Bynum… - … and Apheresis Science, 2019 - Elsevier
Early administration of blood products following severe trauma is pivotal for establishing
hemostasis and achieving successful outcomes. Platelet transfusions, in particular, provide …
hemostasis and achieving successful outcomes. Platelet transfusions, in particular, provide …
Cold platelets for trauma‐associated bleeding: regulatory approval, accreditation approval, and practice implementation—just the “tip of the iceberg”
JR Stubbs, SA Tran, RL Emery, SA Hammel… - …, 2017 - Wiley Online Library
BACKGROUND Laboratory and clinical evidence suggest that cold‐stored platelets (CS‐
PLTs) might be preferable to room temperature platelets (RT‐PLTs) for active bleeding …
PLTs) might be preferable to room temperature platelets (RT‐PLTs) for active bleeding …
Coagulopathy, cryoprecipitate and CRYOSTAT-2: realising the potential of a nationwide trauma system for a national clinical trial
1. Valgimigli M, Bueno H, Byrne RA, et al. 2017 ESC focused update on dual antiplatelet
therapy in coronary artery disease developed in collaboration with EACTS: the task force for …
therapy in coronary artery disease developed in collaboration with EACTS: the task force for …
Refrigerated platelets for the treatment of acute bleeding: a review of the literature and reexamination of current standards
This review is a synopsis of the decisions that shaped global policy on platelet (PLT) storage
temperature and a focused appraisal of the literature on which those discussions were …
temperature and a focused appraisal of the literature on which those discussions were …
Effects of storage time prolongation on in vivo and in vitro characteristics of 4 C–stored platelets
M Stolla, SL Bailey, L Fang, L Fitzpatrick… - …, 2020 - Wiley Online Library
ABSTRACT BACKGROUND Cold (4° C)‐stored platelets are currently under investigation
for transfusion in bleeding patients. It is currently unknown how long cold‐stored platelets …
for transfusion in bleeding patients. It is currently unknown how long cold‐stored platelets …