NF-κB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM2.5 aspiration

T Ku, B Li, R Gao, Y Zhang, W Yan, X Ji, G Li… - Particle and fibre …, 2017 - Springer
Abstract Background PM 2.5 (particulate matter≤ 2.5 μm) is one of the leading
environmental risk factors for the global burden of disease. Whereas increasing evidence …

The association between PM2. 5 exposure and neurological disorders: a systematic review and meta-analysis

P Fu, X Guo, FMH Cheung, KKL Yung - Science of the Total Environment, 2019 - Elsevier
Background Recent systematic review and meta-analyses have tried to identify an
association between PM 2.5 exposure and stroke, but few could find a conclusive and …

Hippocampal inflammation and oxidative stress following exposure to diesel exhaust nanoparticles in male and female mice

M Ehsanifar, Z Montazeri, MA Taheri, M Rafati… - Neurochemistry …, 2021 - Elsevier
Air pollution exposure is among the most prevalent reasons for environmentally-induced
oxidative stress and inflammation, both of which are involved in the development and …

Traffic-related air pollutants (TRAP-PM) promote neuronal amyloidogenesis through oxidative damage to lipid rafts

M Cacciottolo, TE Morgan, AA Saffari… - Free Radical Biology …, 2020 - Elsevier
Traffic-related air pollution particulate matter (TRAP-PM) is associated with increased risk of
Alzheimer Disease (AD). Rodent models respond to nano-sized TRAP-PM (nPM) with …

Ambient air pollution increases the risk of cerebrovascular and neuropsychiatric disorders through induction of inflammation and oxidative stress

O Hahad, J Lelieveld, F Birklein, K Lieb… - International journal of …, 2020 - mdpi.com
Exposure to ambient air pollution is a well-established determinant of health and disease.
The Lancet Commission on pollution and health concludes that air pollution is the leading …

Effects of early postnatal exposure to fine particulate matter on emotional and cognitive development and structural synaptic plasticity in immature and mature rats

J Liu, C Yang, J Yang, X Song, W Han, M Xie… - Brain and …, 2019 - Wiley Online Library
Introduction Fine particulate matter (PM2. 5) is closely associated with many neurological
disorders including neurodegenerative disease, stroke, and brain tumors. However, the toxic …

Direct contact with particulate matter increases oxidative stress in different brain structures

LS Fagundes, AS Fleck, AC Zanchi… - Inhalation …, 2015 - Taylor & Francis
Introduction: Several experimental and epidemiological studies have demonstrated the
neurological adverse effects caused by exposure to air pollution, specifically in relation to …

Exposure to inhaled particulate matter activates early markers of oxidative stress, inflammation and unfolded protein response in rat striatum

R Guerra, E Vera-Aguilar, M Uribe-Ramirez, G Gookin… - Toxicology letters, 2013 - Elsevier
To study central nervous system airborne PM related subchronic toxicity, SD male rats were
exposed for eight weeks to either coarse (32 μg/m 3), fine (178 μg/m 3) or ultrafine (107 …

Coarse particulate matter (PM2.5–10) in Los Angeles Basin air induces expression of inflammation and cancer biomarkers in rat brains

JY Ljubimova, O Braubach, R Patil, A Chiechi, J Tang… - Scientific reports, 2018 - nature.com
Air pollution is linked to brain inflammation, which accelerates tumorigenesis and
neurodegeneration. The molecular mechanisms that connect air pollution with brain …

Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders

LG Costa, TB Cole, K Dao, YC Chang, J Coburn… - Pharmacology & …, 2020 - Elsevier
Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …