Abstract In this Standard of Laboratory Practice we recommend guidelines for therapeutic
monitoring of cardiac drugs. Cardiac drugs are primarily used for treatment of angina …

Digoxin is widely prescribed for the treatment of cardiac conditions (1). Because of its narrow
therapeutic range, digoxin-related toxicity resulting from acute or chronic overdose is …

We describe a time-resolved fluoroimmunoassay for the cardiac glycoside digoxin. The
assay depends on the competitive distribution of Eu3+-labeled anti-digoxin antibodies …

Digoxin is a cardioactive drug with a narrow therapeutic range. Therapeutic drug monitoring
is essential in clinical practice for efficacy as well as to avoid digoxin toxicity. Immunoassays …

Endogenous digoxin-like immunoreactive factors (DLIF) may crossreact with antidigoxin
antibody and falsely elevate immunoassay results. Recently, a new enzyme-linked …

Our objective was to identify commercially available digoxin immunoassays whose cross-
reactivity with digoxin metabolites paralleled the pharmacological activity of the metabolites …

Digoxin is one of the few therapeutic drugs for which antidotal therapy is available (1).
Administration of Fab fragments has successfully been used to reverse the effects of life …

Background We describe a patient with cirrhotic liver disease and atrial fibrillation who was
treated with spironolactone and digoxin. He was hospitalized because of an incidental …

Following digoxin Fab antibody (FAB) administration in digitalistoxic patients, total serum
digoxin concentrations (SDCS) become elevated, but do not correlate with pharmacologic …

The digitalis drugs are plant-derived cardenolide compounds used medicinally for several
hundred years. These drugs elicit inotropic and chronotropic effects on the heart, but they …